[Constrictive pericarditis as a cause of circulatory failure in a pregnant woman]. / Zaciskajace zapalenie osierdzia jako przyczyna niewydolnosci krazenia u ciezarnej.

A case is reported of severe circulatory failure in a pregnant woman caused by previously unrecognized constrictive pericarditis. The effect of haemodynamic changes characteristic of pregnancy on the manifestation of the disease end the importance of echocardiography as a diagnostic method of choice is stressed in cases of cardiac diseases in pregnancy.

[Platelet aggregation in workers chronically exposed to carbon disulfide and subjected to prophylactic treatment with Cynarex]. / Agregacja plytek krwi u pracowników narazonych na przewlekle dzialanie dwusiarczku wegla i poddanych profilaktyce preparatem cynarex.

62 men producing artificial fibres were administered for 2 years an artichoke extract as a preparation called Cynarex, produced by the Herbs Plant, Herbapol" in Wroclaw. The spontaneous and ADP-induced platelets aggregation was examined by the method of Holdrinet et al. The platelets ability to aggregate, whether spontaneously or by induction was found to be statistically significantly reduced. The spontaneous aggregation after two years of Cynarex administration was reduced on average by 51%.

[Influence of carbon disulfide on hemostasis in rabbits. I. Studies on coagulation and fibrinolysis]. / Wplyw dwusiarczku wegla na uklad hemostazy królików. I. Niektóre badania ukladu krzepniecia i fibrynolizy.

Rabbits were exposed to carbon disulphide vapours in the toxicological chamber. Fibrinogen level, antiplasmin activity and soluble fibrin monomer complexes in the blood were increased, fibrinolysis time was prolonged. These disturbances in hemostasis depend on the concentration of carbon disulphide in the inhaled air and on the intoxication time. The authors suggest that these findings depend on the changed lipid metabolism and on the direct antagonistic influence of CS2 on coagulation and fibrynolysis agents.

Platelet aggregation and adhesiveness as well as blood lipids level in dogs treated with di-(1-isoquinolinyl)-di-(pyridyl-2')-butane and carbocromen.

The effect of di-(1-isoquinolinyl)-di-(pyridyl-2')-butane (S-147) on platelet aggregation and adhesiveness as well as on blood lipids level (total lipids, triglycerides, total cholesterol) was tested in mongrel dogs, in comparison with carbocromen. The compounds administered iv (2 mg/kg/day) over 7 days inhibited ADP-induced aggregation, being without depressive influence on platelet adhesiveness. S-147 exhibited slightly stronger effect than carbocromen. The inhibition of platelet aggregation was accompanied by the decrease of serum lipids level.

[Effect of carbon disulfide on hemostasis in rabbits. II. Platelet adhesiveness]. / Wplyw dwusiarczku wegla na uklad hemostazy królików. II. Adhezja plytek krwi.

Rabbits were exposed to carbon disulphide vapour in toxocological chamber. Increased platelet adhesiveness was found in exposed animals, dependent on CS2 concentration in the chamber and duration of intoxication. The authors suggest that the increased platelet adhesiveness may result from lipid metabolism disturbances.