RESUMO
The fifth cranial nerve is the common denominator for many headaches and facial pain pathologies currently known. Projecting from the trigeminal ganglion, in a bipolar manner, it connects to the brainstem and supplies various parts of the head and face with sensory innervation. In this review, we describe the neuroanatomical structures and pathways implicated in the sensation of the trigeminal system. Furthermore, we present the current understanding of several primary headaches, painful neuropathies and their pharmacological treatments. We hope that this overview can elucidate the complex field of headache pathologies, and their link to the trigeminal nerve, to a broader field of young scientists.
Assuntos
Dor Facial/patologia , Cefaleia/patologia , Gânglio Trigeminal/patologia , Nervo Trigêmeo/patologia , Animais , Tronco Encefálico/metabolismo , Tronco Encefálico/patologia , Tronco Encefálico/fisiopatologia , Dor Facial/metabolismo , Dor Facial/fisiopatologia , Cefaleia/metabolismo , Cefaleia/fisiopatologia , Humanos , Gânglio Trigeminal/metabolismo , Gânglio Trigeminal/fisiopatologia , Nervo Trigêmeo/metabolismo , Nervo Trigêmeo/fisiopatologiaRESUMO
The data concerning 2500 allergic patients are analysed and the low incidence of so-called "minor pollens" in respiratory allergopathies is documented. Moreover a frequent association of positivity with the so-called "major allergens" (Grass, Parietaria, Dermatophagoides) was observed. Specific hyposensitizing therapy is advised only in carefully selected patients, those showing perfect agreement between allergological data and clinical symptomatology.
