Noteworthy synthesis strategies and applications of metal-organic frameworks for the removal of emerging water pollutants from aqueous environment.

17 global Sustainable Development Goals (SDGs) were established through the adoption of the 2030 Agenda for Sustainable Development by all United Nations members. Clean water and sanitation (SDG 6) and industry, innovation, and infrastructure (SDG 9) are the SDGs focus of this work. Of late, various new companies delivering metal-organic frameworks (MOFs) have blossomed and moved the field of adsorption utilizing MOFs to another stage. Inside this unique circumstance, this article aims to catch recent advancements in the field of MOFs and the utilizations of MOFs relate to the expulsion of arising contaminations that present huge difficulties to water quality because of their steadiness and possible damage to environments and human wellbeing. Customary water treatment techniques regularly neglect to eliminate these poisons, requiring the advancement of novel methodologies. This study overviews engineering techniques for controlling MOF characteristics for better flexibility, stability, and surface area. A current report on MOFs gathered new perspectives that are amicably discussed in emergent technologies and extreme applications towards environmental sectors. Various applications in many fields that exploit MOFs are being fostered, including gas storage, fluid separation, adsorbents, catalysis, medication delivery, and sensor utilizations. The surface area of a wide range of MOFs ranges from 103 to 104 m2/g, which exceeds the standard permeability of several material designs. MOFs with extremely durable porosity are more significant in their assortment and variety than other classes of porous materials. The work outlines the difficulties encountered in the synthesis steps and suggests ways to make use of MOFs' value in a variety of contexts. This caters to creating multivariate systems enclosed with numerous functionalities, leading to the synthesis of MOFs that offer a synergistic blend of in-built properties and exclusive applications. Additionally, the MOF-related future development opportunities and challenges are discussed.

Oral dysbiosis and risk of gastrointestinal cancers: A systematic review and meta-analysis of longitudinal studies.

BACKGROUND: Poor oral health and oral dysbiosis were found to be associated with cancers, especially of the gastrointestinal (GI) system. But the cause-and-effect relationship and the effect of the risk are not yet known due to scarcity of literature. Understanding such risk relationship can contribute to an integrated multi-disciplinary approach for GI cancer prevention. AIM: The aim of the present systematic review and meta-analysis is to assess the role of oral dysbiosis on increasing the risk of digestive system cancers. OBJECTIVE: To evaluate the effect of poor oral health on increasing the risk of gastrointestinal cancers. METHODS: We conducted a systematic search following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in databases PubMed, Elsevier, Wiley's online library and Web of Science from inception to February 2023 to include recent cohort studies that assessed the association between poor oral health and the risk of cancer. We assessed bias using the New Castle Ottawa scale. We used inferential statistics to describe the effect of oral dysbiosis on gastrointestinal cancers. We performed a sub-group analysis to assess the effect of oral conditions on individual cancers. RESULTS: We included 10 longitudinal studies in the meta-analysis. The overall effect size of poor oral health and GI cancer risk was hazard's ratio (HR) =1.30 (95% CI: [1.14, 1.46]) (p<0.001) (I2 = 68.78). Sub-group analysis indicated that poor oral health increases the risk of esophageal cancer HR=1.61 (95% CI: [1.37, 1.85]), stomach cancer HR=1.33 (95% CI: [1.08, 1.58]), pancreatic cancer HR=1.90 (95% CI; [1.29, 2.50]) and colorectal and hepatocellular carcinoma HR=1.16 (95% CI: [1.08, 1.23]). CONCLUSION: The meta-analysis indicated that poor oral health was significantly associated with increasing the risk of GI cancers.

Cárie Dentária em Pré-Escolares: um Estudo em Áreas Cobertas pela Estratégia Saúde da Família do Recife, PE, Brasil / Dental Caries in Preschoolers: A Study in Areas Assisted by the Family Health Strategy of the city of Recife, PE, Brazil

Objeti vo: Analisar o padrão de distribuição da cárie dentáriaem pré-escolares residentes em áreas assisti das pela EstratégiaSaúde da Família do Recife, Pernambuco, em dois distritossanitários e, estabelecer comparações.Método: Um inquérito epidemiológico de cárie dentária foiconduzido no ano de 2006 em 2020 crianças de 18-36 meses e5 anos de idade cadastradas nas unidades de saúde da famílianos Distritos Sanitários II e IV, Recife/PE. Uti lizou-se o índiceceo-d, segundo padronizações da Organização Mundial deSaúde e do Ministério da Saúde. A amostra foi probabilísti capor conglomerados (famílias) em um estágio. Calculou-sedistribuição de freqüência, testes de comparação de médias(t-Student e ANOVA), de proporções (Qui-quadrado) comnível de signifi cância de 5,0% e fatores de ponderação pararepresentati vidade da amostra. As análises foram produzidaspor distrito e microrregiões.Resultados: Nos dois Distritos as prevalências e médias ceo-dforam elevadas, sendo de 29,7% no total de crianças de 18-36meses e 63,8% aos 5 anos. Entre os Distritos o ceo-d variou de0,99 a 1,15 (18-36 meses) e 3,01 a 3,65 (5 anos). Contudo, asrazões de prevalência não apresentaram diferenças signifi cantesentre distritos e idades. Entre microrregiões, as diferençasna prevalência e severidade ocorreram apenas na idade de 5anos.Conclusão: Os indicadores de cárie uti lizados informama existência de nichos infanti s com piores situações desaúde bucal em áreas pobres de aparente homogeneidadesocioeconômica devendo-se assim reorientar as intervençõescoleti vas e individuais em áreas/microáreas, onde esses índicessão mais elevados...

Objecti ve: To analyze comparati vely the distributi on patt ernof dental caries in preschoolers living in areas assisted by theFamily Health Strategy of the city of Recife, PE, in two sanitarydistricts.Method: An epidemiological survey of dental caries wasconducted in 2006 in 2,020 children aged 18-36 months and5 years enrolled in the Family Health Centers of the SanitaryDistricts II and IV of the city of Recife, PE. The dmft index wasused as recommended by the World Health Organizati onand the Brazilian Ministry of Health. A probabilisti c sampleby conglomerates (families) was used in one stage. It wascalculated frequency distributi on, tests for comparison of themeans (Student’s t-test and ANOVA) and proporti ons (chisquare)with 5.0% signifi cance level, and ponderati on factorsfor sample representati veness. The analyses were produced bydistrict and by microregions.Results: In both districts, the prevalence and dmft means werehigh, being 29.7% among children aged 18-36 months and63.8% among those aged 5 years. Comparing the districts, thedmft ranged from 0.99 to 1.15 (18-36 months) and from 3.01to 3.65 (5 years). However, the prevalence rati os did not showsignifi cant diff erences between districts or ages. Comparing themicroregions, the diff erences in caries prevalence and severityoccurred only at the age of 5.Conclusion: The caries indicators used in this study revealedthe existence of niches of children with worse oral healthconditi ons in poor areas with apparent socioeconomichomogeneity, suggesti ng a reorientati on of collecti ve andindividual interventi ons in areas/microareas in which higherindices are observed...

A paired comparison among siblings of common parents about dental care with and without Down syndrome / Comparação pareada da assistência odontológica entre irmãos de mesmos pais portadores ou não de síndrome de Down

Objetivo: Comparar a assistência odontológica entre irmãos de mesmos pais portadores ou não de síndrome de Down. Método: Um estudo analítico transversal envolvendo 180 indivíduos com Síndrome de Down e 180 irmãos destes sujeitos sem Síndrome de Down, foi conduzido numa escola de ensino especial na cidade de Udaipur, Rajasthan, India. Empregando um modelo de questionário validado, os pais foram solicitados a preencher duas versões do questionário, sendo uma para o filho com Síndrome de Down e outro para o filho com idade mais próxima sem Síndrome de Down. Resultados: Muitos pais apresentaram comportamentos ou experiências diferentes com o filho portador de Síndrome de Down e o respectivo irmão sem Síndrome de Down. As maiores diferenças foram observadas quanto à consulta anual ao dentista (p<0,001), flúor terapia (p<0,001), extrações (p<0,001) e tratamento ortodôntico (p<0,001). As crianças com Síndrome de Down foram menos propensas a visitar o dentista anualmente e a receber flúor terapia e tratamento ortodôntico em comparação aos seus irmãos sem Síndrome de Down. Conclusão: Essa análise pareada sobre diferenças familiares nos comportamentos e experiências de assistência odontológica entre irmãos com e sem Síndrome de Down irmãos demonstrou que crianças com Síndrome de Down têm menor probabilidade de serem levadas ao dentista anualmente, receberem cuidados de prevenção à cárie e tratamento restaurador, e serem submetidas a extrações dentárias.

Objective: To compare dental care among siblings of common parents with and without Down syndrome. Method: A cross sectional analytical study was conducted in 180 mentally retarded subjects with Down syndrome and 180 their siblings without Down syndrome at a special need school in Udaipur city Rajasthan. Using a validated questionnaire, parents were asked to complete two versions of the questionnaire one for their child with Down syndrome and another for the siblings closest in age without Down syndrome. Results: Many respondents showed different behavior or experiences to their child with Down syndrome and a sibling without Down syndrome. The greatest differences were observed for yearly consultation to the dentist (p<0.001), fluoride therapy (p<0.001), extraction (p<0.001) and orthodontic treatment (p<0.001). Down syndrome subjects were less likely to consult a dentist yearly and less likely to receive fluoride therapy and orthodontic treatment in comparison to their siblings without Down syndrome. Conclusion: This paired analysis of within family differences in dental care behaviors and experiences for subject with Down syndrome and non Down syndrome siblings demonstrated that there are differences, subject with Down syndrome are less likely to consult a dentist yearly, less likely to receive caries-preventive and restorative care and less likely to have had a dental extraction.

Tobacco as risk factor for periodontal disease in green marble mine laborers of Rajasthan, India

Aim: To determine the effect of tobacco usage on the severity of periodontal disease in green marble mine laborers. Methods: Marble mine laborers (n=585) aged 15–54 years were selected from four geographic zones in green marble mines area using a stratifiedrandom sampling procedure. A total of 517 (88%) laborers participated in the study. The sample were classified as tobacco users, non users, occasional users, ex users and the data regarding form, duration and frequency of tobacco consumption was also collected by personal interviews. Periodontal status was assessed by community periodontal index. Results: Nearly three fourth (71.9%) of the population was tobacco users. Among the smokers, bleeding and calculus accounted to 33% each whereas the prevalence of these periodontal indicators was 38% and 44% respectively among smokeless tobacco users. Logistic regression analyses revealed that smokeless tobacco users were more liable for presence of periodontal pockets than smokers. Duration had a significant influence with users since more than 20 years being liable for presence of pockets at least twice (OR = 2.625, 95% CI 1.529 – 4.507) than the <5 years group. The odds ratio for presence of periodontal pockets increased by 2.143 (95 % CI 1.060 – 4.333) and 5.596 (95 % CI 2.901 – 10.639) for users of 6 – 10 units/ day and more than 10 units/day than the 1-2 times/day category. Conclusions: Tobacco usage had a significant impact on the severity of periodontal disease with users being more likely to present periodontal pockets than non users. Moreover, the risk of periodontal pockets increased as the duration and frequency of tobacco consumption increased.