RESUMO
The physiological changes during pregnancy may increase the risk of complications in pregnant women with coronavirus disease 2019 (COVID-19). Vitamin D is a fat-soluble secosteroid hormone and its role in immunity is appears to be of particular importance in this recent pandemic. Nevertheless, there is little research about the role of vitamin D levels regarding COVID-19 in pregnant women to date. This study aimed to establish a relationship between serum 25-hydroxyvitamin D (25(OH)D) levels in pregnant women and COVID-19. A comparative case-control study was performed with a study population of 256 pregnant women (82 pregnant women with infection and 174 women in control group). Serum 25(OH)D levels were significantly lower in pregnant women with COVID-19 infection than in those without infection. In addition, 89% of COVID-19-positive pregnant women had 25(OH)D deficiency, while in the control group the percentage was 75.30%, finding statistically significant differences (ORa = 2.68; 95% CI 1.19-6.06; p = 0.01). Our results find a relationship between vitamin D deficiency in pregnant women and COVID-19 infection. This finding could be relevant for actual clinical practice. Thus, more research is needed in this field.
Assuntos
COVID-19 , Complicações na Gravidez , Deficiência de Vitamina D , COVID-19/epidemiologia , Estudos de Casos e Controles , Feminino , Humanos , Gravidez , Complicações na Gravidez/epidemiologia , Gestantes , Vitamina D , Deficiência de Vitamina D/epidemiologia , VitaminasRESUMO
Objetivo: Estudiar exhaustivamente los datos obtenidos en los partos del año 2016 en el Hospital Comarcal de Melilla. Método: Estudio descriptivo, retrospectivo de corte transversal. Para el análisis de los datos se utilizó el programa estadístico SPSS 22.0. Resultados: El total de la muestra fue de 2601 partos, el 40.8 % fueron embarazos controlados, frente al 59.2 % de embarazos no controlados. De dichos partos, el 75.7 % terminaron siendo partos eutócicos, el 16.8 % acabaron en cesárea y el 7.6 % fueron partos distócicos. Conclusiones: En nuestro estudio el control o no de la gestación tuvo asociación estadísticamente significativa con la terminación del parto. Se obtuvo en las gestantes no controladas un mayor número de casos de partos eutócicos y de instrumentales que en las gestantes controladas, y menor número de cesáreas. Sin embargo, en nuestro estudio el control del embarazo no se asocia a peores cifras en el test de Apgar al minuto y a los 5 minutos, ni a mayor morbilidad perineal tras el parto
Aim: To study in depth the data obtained from the births in 2016 at the Hospital Cormarcal de Melilla (Spain). Method: A retrospective, cross sectional, descriptive study. For the data analysis, the statistic programme SPSS 22.0 was used. Results: The study sample consisted of 2601 births, the 40.8 % were controlled pregnancies, compared to the 59.2 % that were non-controlled pregnancies. From such births the 75.7 % ended as normal births, the 16.8 % ended by caesarean sections and the 7.6 % were complicated births. Conclusion: It is remarkable that in our study whether the pregnancy was controlled or non-controlled had a significant statistic association with the birth result, obtaining a higher number of normal and instrumental deliveries in the controlled pregnancies and a lower number of caesarean sections, however, the management of pregnancy in our study it is not associated with worst Apgar scores at one minute and 5 minutes, or with increased perineal morbidity after birth
