Prophylaxis for preventing venous thromboembolism in knee arthroscopy and soft tissue reconstruction: consensus statements from an international panel of experts.

PURPOSE: There is a lack of consensus regarding need for Venous Thrombo Embolism (VTE) prophylaxis following arthroscopic knee surgery and open soft tissue knee reconstruction. Clear cut guidelines like ones for trauma surgery and arthroplasty do not exist and the published literature is limited to case reports with a few society guidelines. Given this lack of consensus, we conducted a modified Delphi questionnaire of international experts to provide recommendations on this topic. METHODS: The consensus statements were generated using an anonymised 3 round modified Delphi questionnaire, sent to an international panel of 38 knee surgeons, with an 80% agreement being set as the limit for consensus. The responses were analysed using descriptive statistics with measures like mode, median and box plots. Feedback was provided to all panelists based on responses from the previous rounds to help generate the consensus. RESULTS: Six consensus statements were generated after the three rounds of Delphi. Patient factors, prolonged surgery duration and family history of thrombogenic events emerged as the main points to be taken into consideration for prophylaxis. CONCLUSION: It was established through this study, that there exists a select group of patients undergoing arthroscopic surgery that justify the usage of VTE prophylaxis. The expert responses to most of the questions in different scenarios favoured usage of VTE prophylaxis based on patient factors like advanced age, past history of VTE, smoking, oral contraceptive use etc. LEVEL OF EVIDENCE: Level V.

Improvement of Orthopedic Residency Programs and Diversity: Dilemmas and Challenges, an International Perspective.

BACKGROUND: To date, little has been published comparing the structure and requirements of orthopedic training programs across multiple countries. The goal of this study was to summarize and compare the characteristics of orthopedic training programs in the U.S.A., U.K., Canada, Australia, Germany, India, China, Saudi Arabia, Russia and Iran. METHODS: We communicated with responders using a predetermined questionnaire regarding the national orthopedic training program requirements in each respondent's home country. Specific items of interest included the following: the structure of the residency program, the time required to become an orthopedic surgeon, whether there is a log book, whether there is a final examination prior to becoming an orthopedic surgeon, the type and extent of faculty supervision, and the nature of national in-training written exams and assessment methods. Questionnaire data were augmented by reviewing each country's publicly accessible residency training documents that are available on the web and visiting the official website of the main orthopedic association of each country. RESULTS: The syllabi consist of three elements: clinical knowledge, clinical skills, and professional skills. The skill of today's trainees predicts the quality of future orthopedic surgeons. The European Board of Orthopedics and Traumatology (EBOT) exam throughout the European Union countries should function as the European board examination in orthopedics. We must standardize many educational procedures worldwide in the same way we standardized patient safety. CONCLUSION: Considering the world's cultural and political diversity, the world is nearly unified in regards to orthopedics. The procedures (structure of the residency programs, duration of the residency programs, selection procedures, using a log book, continuous assessment and final examination) must be standardized worldwide, as implemented for patient safety. To achieve this goal, we must access and evaluate more information on the residency programs in different countries and their needs by questioning them regarding what they need and what we can do for them to make a difference.

Does Prior Failed Debridement Compromise the Outcome of Subsequent Two-Stage Revision Done for Periprosthetic Joint Infection Following Total Knee Arthroplasty?

BACKGROUND: There has been a debate regarding the outcomes of 2-stage revision total knee arthroplasty (TKA) when debridement, antibiotics, irrigation, and implant retention (DAIR) had been carried out previously. The purpose of this study is to evaluate the influence of prior failed DAIR (F-DAIR) on the outcomes of 2-stage revision TKA done for periprosthetic joint infection (PJI). METHODS: This is a retrospective study of a consecutive series of 184 knees that completed 2-stage revision TKA for PJI, operated by a single surgeon between January 2000 and July 2011. The cohort was divided into 2 groups: (1) with previous F-DAIR (88 knees) and (2) direct 2-stage revision (96 knees). RESULTS: At an average follow-up of 5.3 years, the failure rate was 23.86% (21/88 knees) in the F-DAIR group and 15.62% (15/96) in the direct 2-stage revision group. Prior F-DAIR procedure was associated with approximately twice the risk of failure compared to direct 2-stage surgery (hazards ratio 1.94, 95% confidence interval 1.01-3.714, P = .047). Excluding PJIs caused by methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, and Pseudomonas from analysis revealed similar failure rates between the 2 groups. The Knee Society Clinical Score, Knee Society Functional Score, and final range of motion at final follow-up were lower in the F-DAIR group. Incidence of culture negativity and infection with resistant organisms was higher in the F-DAIR group. The rates of eradication of methicillin-resistant Staphylococcus aureus and Pseudomonas infection were much lower in the F-DAIR group. CONCLUSION: A failed prior DAIR results in higher failure rates, lower functional outcome, and increased risk of wound-related complications.

A Comparative Study on the Long-Term Outcome of Total Knee Arthroplasty Performed for Knees Stiff in Extension and Those Stiff in Flexion.

BACKGROUND: Patients with chronic stiff knee with extremely restricted arc of motion (AOM ≤ 20°) may present with stiffness either in extension (stiff in extension [SE]) or in flexion (stiff in flexion [SF]). The difference in the functional outcome after total knee arthroplasty between these 2 groups has not been elaborated in literature. METHODS: We retrospectively analyzed 96 patients (115 knees), who had undergone total knee arthroplasty between January 1990 and December 2010 for stiff or spontaneously ankylosed knees (AOM ≤ 20°). This included 51 knees in SE group and 64 knees in SF group. RESULTS: The average duration of follow-up was 9.7 years (2-17.5 years). The total AOM improved from an average of 10.9° ± 7.4° preoperatively to 86.5° ± 13.5° postoperatively in SE group and 8.7° ± 6.8° to 92.2° ± 16.8° in the SF group. The mean Knee Society Score in the SE group improved from 23.2 ± 5.7 preoperatively to 74.1 ± 8.9 postoperatively and that of SF group from 14 ± 5.2 to 71.2 ± 12.5. At 3 months follow-up, Knee Society Score for SE group were higher than that for SF group (P = .03). This difference was not noted beyond 1 year. Complications were noted in 24 (20.9%) knees-10 (23.5%) in SE group and 14 (21.9%) in SF group. CONCLUSION: The maximum mean AOM achieved was higher in SF group but the incidence of residual flexion contracture was also higher as compared to SE group. The long-term functional outcome scores in SE and SF groups are similar.

Are the Outcomes of Revision Knee Arthroplasty for Flexion Instability the Same as for Other Major Failure Mechanisms?

BACKGROUND: Aseptic loosening, infection, and flexion instability have emerged as the leading etiologies for revision after total knee arthroplasty (TKA). Although studies have reported improved outcomes after revision TKA, the relative functional and clinical outcomes of patients revised for flexion instability and other failure etiologies have not been extensively reported. The aim of the study was to compare the functional and patient-reported outcomes of revision TKA for the common failure etiologies. METHODS: We retrospectively reviewed records of 228 consecutive cases of revision TKA from 2008 to 2014. Revisions performed for aseptic loosening (n = 53), septic revisions (n = 48), and isolated flexion instability (n = 45) with a minimum of 18 months follow-up were included for analysis. Revision for all other etiologies (n = 82) were excluded. The Modified Knee Society Score (KSS), KSS Function, and Western Ontario and McMaster Universities Osteoarthritis Index were recorded for all cases. A 7-point Likert scale was used to record patient's perception of outcomes after revision surgery and analyzed based on etiology. RESULTS: Although all groups showed improvement in outcome after revision TKA, the changes in Modified KSS and KSS-Function varied according to the etiology of failure of the primary procedure with the smallest improvement being reported by the flexion instability group. CONCLUSION: Patients undergoing revision for isolated flexion instability have less improvement in functional outcome as compared with other etiologies. We hypothesize this is due to a higher baseline preoperative knee function in the flexion instability group.

Arthroscopic All-Inside Posterior Cruciate Ligament Reconstruction: Overcoming the "Killer Turn".

One of the most challenging arthroscopic surgical procedures is posterior cruciate ligament (PCL) reconstruction. PCL injuries account for 20% of all knee ligament-related injuries. These may be isolated or occur as part of poly-ligament injuries. With the possibility of PCL reconstruction with the all-inside technique, there has been a surge in interest in treating PCL injuries. With the PCL being one of the strongest ligaments in the body and a primary restraint to posterior translation of the tibia, the need for PCL reconstruction is being more and more recognized. Surgeons often find it difficult to negotiate the so-called killer turn while attempting arthroscopic PCL reconstruction. We describe the use of the GraftLink graft construct through the posteromedial portal in 7 patients (6 male and 1 female patient) with isolated PCL injuries, which we believe not only allows us to perform the all-inside PCL reconstruction but also does away with the difficulty of the killer turn encountered while performing the arthroscopic PCL reconstruction.

Wear Patterns in Knee Articular Surfaces in Varus Deformity.

This study was performed to study the relationship between the degree of varus deformity of osteoarthritic knees and the anatomic distribution of cartilage pathology. Bone wafers resected from the distal femur and proximal tibia were obtained from 107 patients (195 knees) with primary varus osteoarthritis. Severity and distribution of joint damage was scored for each articular surface and related to potential prognostic factors, including varus deformity, the ligamentous status of the knee, age, gender and BMI. There was highly significant association between varus angulation of the knee and the total damage score for the tibia (P=0.001), but not the femur (P=0.2947). The degree of deformity, and not the status of the ACL alone, determines wear pattern and provides insight for preoperative planning of TKA.

Patellar Tendon Reconstruction in Total Knee Arthroplasty: A New Technique.

Patellar tendon disruption is one of the most dreaded complications following total knee arthroplasty (TKA) impacting both implant function and implant longevity. To overcome the concerns regarding allografts and improve outcomes with augmentation techniques, we describe a technique, which we have successfully used over the past 4 years with good results. Seven patients underwent reconstruction for patellar tendon disruption using our technique from a cohort of eight patients. Extensor lag improved from a mean of 40 degrees to less than 5 degrees postoperatively. Range of motion improved from a mean of 105 degrees to 115 degrees of flexion. There was improvement in Knee Society Functional Score from a preoperative mean of 30 to 75 points. The Knee Society Pain Score, however, did not show much improvement. We believe our technique to be a solution to the difficult problem of patellar tendon ruptures after TKA and we continue to perform this procedure.

Revision total knee arthroplasty for septic versus aseptic failure.

PURPOSE: To compare the medium-term outcome of revision total knee arthroplasty (TKA) for septic versus aseptic failure. METHODS: Records of 142 patients who underwent revision TKA by a single senior surgeon for septic (n=65) or aseptic (n=77) failure were reviewed. In the septic group, 67 knees in 42 women and 23 men were included. In the aseptic group, 88 knees in 51 women and 26 men were included. The Knee Society Score was measured. The Kaplan Meier survival curve at months 36, 60, and 95 was plotted, with revision as the end point. The survival rates at each specific time point between the 2 groups were compared using the Z test. RESULTS: The Knee Society Scores improved 18% from 51 to 69 in the septic group and 18% from 52 to 70 in the aseptic group (p=0.72). The range of motion improved 30% from 72 to 102 degrees in the septic group and 39% from 62 to 100 degrees in the aseptic group (p<0.001). CONCLUSION: Results of the 2 groups were similar in terms of the Knee Society Score, range of motion, and the Kaplan-Meier survivorship.

Outcomes of total knee arthroplasty following high tibial osteotomy.

BACKGROUND: Total knee arthroplasty (TKA) following high tibial osteotomy (HTO) is a technically demanding procedure with varying results. The purpose of our study was to analyze the clinicoradiological results of TKA following HTO and to identify the factors that may influence the final outcome. MATERIALS AND METHODS: 55 patients (58 knees) who had undergone a previous HTO were treated with a TKA from 1991 to 2009. There were 34 female and 21 male patients. The average age was 61.9 years (range 52-82 years) and the average weight was 79.5 kg (range 54-106 kg), with an average body mass index of 29.6 (range 21.8-34.6) at the time of TKA. The knee society scores (KSSs) and knee society functional scores were evaluated for every patient pre and postoperatively and the results evaluated. RESULTS: The mean period of followup was 11.2 years (range 3-18 years) and the patients were followed up every year. The average KSS score at final followup improved from 38.5 (range 0-80 points) preoperatively to 88.5 postoperatively (range 35-95 points) (P < 0.05). The mean femorotibial angle corrected from 6.8 degrees (range 5-12°) varus preoperatively to a valgus of 4.4 (2-8°) degrees postoperatively. The average joint line height improved to an average of 9.6 mm (range 4.4-22 mm) (P < 0.01) at the last followup. The average Insall Salvatti Ratio also improved (average 1.11 preoperative - 1.21 average postoperative) (P < 0.05). The average range of motion improved to 108° (range 85°-125°) from 76° preoperative (range 55°-100°) (P < 0.01). CONCLUSION: Although TKA postHTO is a demanding surgery however, with newer component designs, results are comparable to primary TKA. Technical difficulties in exposure can sometimes lead to component malpositioning, which can affect the final outcome. Inadequate soft tissue balancing and limb malalignment should always be kept in mind. Regular followup to look for evidences of loosening is advised in such patients].

Midterm results of cruciate retaining total knee arthroplasty in patellectomized patients.

BACKGROUND: Total knee arthroplasty (TKA) in patellectomized patients gives inferior results when compared with those in which the patella is present. The literature is ambiguous about the role of cruciate retaining or sacrificing implants for these knees. In this study, we assessed the midterm results of TKA in patellectomized knees using a cruciate retaining implant. MATERIALS AND METHODS: Thirty three patients with a prior patellectomy underwent a cruciate retaining TKA and were followed up for an average of 9.3 years (range 2-14 years). At each followup visit, they were evaluated clinically, radiologically and by the Hospital for Special Surgery Scoring System. RESULTS: Twenty one knees did not have any pain or difficulty in climbing stairs, 10 knees were slightly painful on stairs but pain free on walking on flat ground and two knees experienced mild to moderate pain on walking up and down stairs as well as on flat ground. The average range of motion preoperatively was 87°, which postoperatively increased to 118°. The average Hospital for Special Surgery Knee scores increased from 52 to 89 points. None of the knees showed any progressive radiolucencies or evidence of any loosening/osteolysis or fractures in followup. CONCLUSION: Cruciate retaining TKA offers good results at midterm followup in patients with a prior patellectomy.

Total knee arthroplasty in extra articular deformities: A series of 36 knees.

BACKGROUND: The presence of extra articular deformities either in the femur or the tibia with arthritis of the knee makes total knee arthroplasty (TKA) technically demanding. The purpose of this study is to report outcomes with Total Knee Arthroplasty in patients with arthritis of the knee associated with extra articular deformity by intraarticular resection and soft tissue balancing. MATERIALS AND METHODS: Thirty six knees (32 patients) who had arthritis of the knee associated with extra articular deformity, underwent total knee arthroplasty between 1999 and 2006 were included in this retrospective analysis. All patients had intraarticular resection with soft tissue balancing to correct the deformity. Full length weight bearing anteroposterior X-rays, Knee society scores, and Knee range of motion was recorded pre- and postoperatively. RESULTS: The mean period of followup was 85 months (range 42-120 months). The deformities amenable to correction by intraarticular resection in our series were Femur- Coronal plane 11°-18° (mean 16.2°) Saggital plane 0°-15° (mean 10.1°) Tibia - Coronal plane 12°-24° (mean 21°). There was an improvement in the range of motion from mean of 54° preoperatively to 114° postoperatively (P value < 0.05). The Knee Society- Knee Score improved from 37 points to 85 points postoperatively (P value < 0.05). The functional score improved from a mean value of 19 to a mean of 69.5 at followup (P < 0.01). The preoperative hip knee ankle angle in the coronal plane improved from a mean of 14° ± 2° varus (26° varus to 4° valgus) to a mean of 2° ± 0.6° varus (6° varus to 2° valgus). CONCLUSION: With a good preoperative planning and templating, intraarticular bone resection and good soft tissue balancing both in flexion and extension, correction would be possible in majority of extraarticular deformities.

Mid-term results of rotating hinge knee prostheses.

Between December 2002 and December 2007, we retrospectively assessed the mid term results of the Nexgen rotating hinge prosthesis in the hands of a single surgeon in difficult primary and complex revision situations. Forty four patients (46 knees) were included in the study: they were followed for an average of 62 months. Knee Society knee score improved from a preoperative mean value of 47 to a mean value of 81 at follow-up (p < 0.05) whereas the mean function score improved from 17 (0-40) to 67.5 (0-90) at follow-up (p < 001). Mean flexion range improved from 65 degrees to 96 degrees at follow-up (p < 0.05). In conclusion, rotating hinge knees gave satisfactory results in difficult revision situations associated with major bone loss, instability or periprosthetic fracture. They also provided satisfactory results in selected cases of advanced primary osteoarthritis.

Evaluation of the posterior cruciate ligament in long standing cruciate retaining total knee arthroplasty.

We evaluated the status of the posterior cruciate ligament in 52 knees with a cruciate retaining total knee arthroplasty 11 years after the index surgery. The evaluation consisted of the Knee Society scores, clinical examination of antero-posterior laxity using the Lachmann test and posterior drawer test. We also used the KT 1000 device, stress radiographs and MRI scan to corroborate this. Three knees were found to be lax clinically and had a posterior tibial shift on radiographs. The MRI scans were able to delineate the posterior cruciate ligament in 86% of the knees. Eleven years after surgery, clinical, radiological and MRI scans when assessed in combination demonstrated the presence of a stable posterior cruciate ligament in 94%.

Long-term results of total knee arthroplasty for valgus knees: soft-tissue release technique and implant selection.

PURPOSE: To report long-term results of total knee arthroplasty (TKA) for valgus knees. METHODS: 34 women and 19 men aged 39 to 84 (mean, 74) years with valgus knees underwent primary TKA by a senior surgeon. Of the 78 knees, 43, 29, and 6 had type-I, type-II, and type-III valgus deformities, respectively. A preliminary lateral soft-tissue release was performed, and the tibia and femur were prepared. The tight lateral structures were released using the pie-crusting technique. In 92% of the knees, cruciate-retaining implants were used. In knees with severe deformity and medial collateral ligament insufficiency, the posterior cruciate ligament was sacrificed and constrained implants were used. The Hospital for Special Surgery (HSS) knee score was assessed, as were tibiofemoral alignment, range of motion, stability, and evidence of loosening or osteolysis. RESULTS: Patients were followed up for 8 to 14 (mean, 10) years. All knees had a good patellar position and were clinically stable in both mediolateral and anteroposterior planes. No radiolucency was noted. The mean HSS knee score improved from 48 to 91 (p<0.001). The mean tibiofemoral alignment improved from valgus 20 to 5 degrees (p<0.001). The mean range of motion improved from 65 to 110 degrees (p<0.001). One patient developed a deep infection at year 4, and 2 had periprosthetic fractures at years 6 and 8. CONCLUSION: Adequate lateral soft-tissue release is the key to successful TKAs in valgus knees. The choice of implant depends on the severity of the valgus deformity and the extent of soft-tissue release needed to obtain a stable, balanced flexion and extension gap, in order to achieve minimal constraint with maximum stability.