RESUMO
The cost, side effect profile, and required weekly blood draws associated with clozapine may dissuade some clinicians from prescribing this atypical neuroleptic to mentally retarded patients. All publications on clozapine use in mentally retarded patients are reviewed and the treatment of 10 such patients is described, bringing the total number of published cases to 84. Clozapine is efficacious and well tolerated in this population and should be considered for those patients with psychosis or bipolar illness who are intolerant of or unresponsive to other agents.
Assuntos
Antipsicóticos/uso terapêutico , Clozapina/uso terapêutico , Deficiência Intelectual/psicologia , Adulto , Antipsicóticos/efeitos adversos , Transtorno Bipolar/complicações , Transtorno Bipolar/tratamento farmacológico , Transtorno Bipolar/psicologia , Clozapina/efeitos adversos , Feminino , Seguimentos , Humanos , Deficiência Intelectual/complicações , Masculino , Pessoa de Meia-Idade , Escalas de Graduação Psiquiátrica , Transtornos Psicóticos/complicações , Transtornos Psicóticos/tratamento farmacológico , Transtornos Psicóticos/psicologiaRESUMO
Physicians who treat women of childbearing age may encounter the presentation of psychosis in a pregnant woman that presents special problems in diagnosis and treatment, particularly ethical and legal considerations that center on the rights of the mother as well as the continually evolving definition of fetal rights. This article represents a collaborative effort to address these considerations. Representative case material from the treatment of a psychotic pregnant patient is presented with a focus on the nature of the contractual relationship of the treating physician with the mother and fetus.
