Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
J Mech Behav Biomed Mater ; 133: 105323, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35816862

RESUMO

In this paper, a visco-hyperelastic model representing the mechanical behavior of the human mandibular periosteum as an anisotropic and homogeneous material is identified. Different models, extracted from the literature, are tested and associated in order to describe the elastic and visco-elastic contributions of the cellular matrix on one hand and the collagen fibers on the other hand. The parameters of these models are determined using five human mandibular periosteum. Each harvested sample is cut and tested, at two different velocities, either longitudinally or transversely to collagen fibers main direction. The hyperelastic and visco-elastic contributions of the cellular matrix are extracted using tensile tests performed transversely. The hyperelastic and visco-elastic contributions of the collagen fibers are extracted using tensile tests performed longitudinally. In a second time, the identified combination of models is validated using twelve samples only tested longitudinally. The selected combination uses the simplified Rivlin's 2nd order law to model the hyper-elasticity of the cellular matrix, the Kulkarni's law to model its visco-elasticity contribution, and the Kulkarni's laws to model the whole contributions of collagen fibers.


Assuntos
Modelos Biológicos , Periósteo , Colágeno , Elasticidade , Humanos , Estresse Mecânico
2.
Biomech Model Mechanobiol ; 19(2): 461-470, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31512012

RESUMO

Knowledge of mandibular periosteum mechanical properties is fundamental for understanding its role in craniofacial growth, in trauma and bone regeneration. There is a lack in the literature regarding mechanical behavior of the human periosteum, including both experimental and modeling aspects. The proposed study involves tensile tests of periosteum samples from different locations including two locations of human mandibular periosteum: lingual and vestibular, compared with samples from various locations of the calvarial periosteum. We propose to analyze the tensile response of the mandibular periosteum using a model, initially applied on the skin, and based on a structural approach involving the mechanical properties of the corrugation of the collagen. Two different approaches for the model parameters' identification are proposed: (1) identification from experimental curve fitting and (2) identification from histological study. This approach allows us to compare parameters extracted from the traction test fitting to structural parameters measured on periosteum histological slices. Concerning experimental aspects, we showed significant differences, in terms of stiffness, between calvarial and mandibular periostea. (The mean final stiffness is [Formula: see text] for the mandible versus [Formula: see text] for the calvaria.) About modeling, we succeed to capture the correct mechanical behavior for the periosteum, and the statistical analysis showed that certain parameters from the geometric data and traction data are significantly comparable (e.g., [Formula: see text] for [Formula: see text]). However, we also observed a discrepancy between these two approaches for the elongation at which the fibril has become straight ([Formula: see text]).


Assuntos
Mandíbula/anatomia & histologia , Modelos Biológicos , Periósteo/anatomia & histologia , Crânio/anatomia & histologia , Colágeno/química , Humanos , Estresse Mecânico , Resistência à Tração
3.
Int J Numer Method Biomed Eng ; 34(10): e3117, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29905015

RESUMO

The aortic valve is normally composed of 3 cusps. In one common lesion, 2 cusps are fused together. The conjoined area of the fused cusps is termed raphe. Occurring in 1% to 2% of the population, the bicuspid aortic valve (BAV) is the most common congenital cardiac malformation. The majority of BAV patients eventually require surgery. There is a lack in the literature regarding modeling of the raphe (geometry and material properties), its role and its influence on BAV function. The present study aims to propose improvements on these aspects. Three patient-specific finite element models of BAVs were created based on 3D trans-esophageal echocardiography measurements, and assuming age-dependent material properties. The raphe was initially given the same material properties as its underlying cusps. Two levels of validation were performed; one based on the anatomical validation of the pressurized geometry in diastole (involving 7 anatomical measures), as simulated starting from the unpressurized geometry, and the other based on a functional assessment using clinical measurements in both systole and diastole (involving 16 functional measures). The pathology was successfully reproduced in the FE models of all 3 patients. To further investigate the role of the raphe, 2 additional scenarios were considered; (1) the raphe was considered as almost rigid, (2) the raphe was totally removed. The results confirmed the interpretation of the raphe as added stiffness in the fused cusp's rotation with respect to the aortic wall, as well as added support for stress distribution from the fused cusps to the aortic wall.


Assuntos
Valva Aórtica/anormalidades , Análise de Elementos Finitos , Doenças das Valvas Cardíacas/fisiopatologia , Algoritmos , Aorta/anatomia & histologia , Aorta/fisiopatologia , Valva Aórtica/fisiopatologia , Doença da Válvula Aórtica Bicúspide , Fenômenos Biomecânicos , Diástole/fisiologia , Ecocardiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Cardiovasculares , Índice de Gravidade de Doença , Sístole/fisiologia , Valva Tricúspide/fisiologia
4.
J Biomech ; 67: 166-171, 2018 01 23.
Artigo em Inglês | MEDLINE | ID: mdl-29217092

RESUMO

Modeling human-object interactions is a necessary step in the ergonomic assessment of products. Fingertip finite element models can help investigating these interactions, if they are built based on realistic geometrical data and material properties. The aim of this study was to investigate the fingertip geometry and its mechanical response under compression, and to identify the parameters of a hyperelastic material property associated to the fingertip soft tissues. Fingertip compression tests in an MRI device were performed on 5 subjects at either 2 or 4 N and at 15° or 50°. The MRI images allowed to document both the internal and external fingertip dimensions and to build 5 subject-specific finite element models. Simulations reproducing the fingertip compression tests were run to obtain the material property parameters of the soft tissues. Results indicated that two ellipses in the sagittal and longitudinal plane could describe the external fingertip geometry. The internal geometries indicated an averaged maximal thickness of soft tissues of 6.4 ±â€¯0.8 mm and a 4 ±â€¯1 mm height for the phalanx bone. The averaged deflections under loading went from 1.8 ±â€¯0.3 mm at 2 N, 50° to 3.1 ±â€¯0.2 mm at 4 N, 15°. Finally, the following set of parameters for a second order hyperelastic law to model the fingertip soft tissues was proposed: C01=0.59 ±â€¯0.09 kPa and C20 = 2.65 ±â€¯0.88 kPa. These data should facilitate further efforts on fingertip finite element modeling.


Assuntos
Dedos/diagnóstico por imagem , Análise de Elementos Finitos , Imageamento por Ressonância Magnética , Fenômenos Mecânicos , Adulto , Fenômenos Biomecânicos , Humanos , Masculino , Modelos Biológicos , Pressão , Estresse Mecânico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...