RESUMO
Background: Selective serotonin reuptake inhibitors are a very common choice of antidepressive drug-therapy during pregnancy. In up to 30% of cases, they have been found to cause neonatal abstinence syndrome in newborn infants. Although often both time-limiting and self-limiting, severe symptoms of neonatal abstinence syndrome (NAS) can occur. Methods/Results: We report a term male infant suffering from a severe brief resolved unexplained event caused by his mother's sertraline intake during pregnancy. Conclusions: Newborn infants exposed to selective serotonine reuptake inhibitors (SSRIs) during pregnancy should be evaluated very carefully concerning NAS and monitored for NAS symptoms for a minimum of 72â»96 h, or until symptoms have fully recovered using standardized protocols. There is a risk of severe NAS symptoms which might occur, and this circumstance should be discussed with the parents and taken into account before administering the drug.
RESUMO
This article aims to describe the pathophysiology of glucose metabolism in newborns of mothers with diabetes in pregnancy, the clinical signs of diabetic fetopathy and hypoglycaemia of the newborn, clinical practical procedures of post-partum blood glucose measurement and definition of hypoglycaemia, as well as prophylaxis and treatment of postpartal hypoglycaemia. In studies, newborns have been described with possibly severe mental retardation in the first years of life after post-partum recurrent hypoglycaemia with or without symptoms. Therefore, it is indicated to measure blood glucose levels regularly on the first day of life. Finally a flowchart for the measurement of glucose and therapy in newborns is presented.
