RESUMO
Objective: Vaccine development, distribution, and immunization of large populations have been identified as vital mitigation strategies for curbing the spread of COVID-19. However, vaccine hesitancy is a major barrier to this. The knowledge and perception of COVID-19 vaccines can improve vaccine acceptance. The purpose of this study was to assess medical students' knowledge, attitude, and perception of COVID-19 vaccines. Methods: This study was a cross-sectional web-based survey conducted among undergraduate students from the faculties of Basic medical sciences and Clinical sciences, University of Uyo, Akwa Ibom State, Nigeria. The students' knowledge was ranked as excellent (>70%), good (50-69%) and poor (<50%) while perception was categorized into positive (>50%), and negative (<50%). The difference in knowledge based on demographics was analyzed using the Independent sample t-test. The association between demographics, and students' perception was carried out using the Chi-square and Fisher's Exact tests. Analyses were conducted using SPSS software version 25. Results: A total of 233 students consented to participate in the study out of which 51.1% were female. Forty-eight students (20.6%) had good knowledge while 41.2% of the participants accepted to take the COVID-19 vaccine. Positive perception was reported among 51.1% (119) of the students. Conclusion: There was poor knowledge and positive perception among majority of the students. Educational intervention in form of training should be done to improve medical students' knowledge and perception toward COVID-19 vaccination.