RESUMO
We report the case of an infant with cytomegalovirus (CMV) infection who developed a nosocomial sepsis of mixed etiology. Fever failed to decrease despite long-time and sustained antibiotic therapy. Treatment with an antiviral agent following the detection of CMV antibody of the IgM class resulted in clinical improvement and subsequent full recovery. We suggest that the diagnosis of CMV infection should be considered even in immunocompetent patients in whom antibiotic therapy fails.
Assuntos
Infecção Hospitalar/microbiologia , Infecções por Citomegalovirus/diagnóstico , Citomegalovirus/isolamento & purificação , Febre/virologia , Anticorpos Antivirais/isolamento & purificação , Bacteriemia/diagnóstico , Bacteriemia/microbiologia , Infecção Hospitalar/diagnóstico , Infecção Hospitalar/virologia , Citomegalovirus/imunologia , Infecções por Citomegalovirus/complicações , Infecções por Citomegalovirus/imunologia , Diagnóstico Diferencial , Feminino , Humanos , Imunoglobulina M/sangue , Lactente , Infecções Estafilocócicas/diagnóstico , Infecções Estreptocócicas/diagnóstico , Fatores de TempoRESUMO
Iatrogenic and traumatic cerebromeningitis infections are increasing in frequency in the last two decades. Retrospective analysis of 87 patients iatrogenic and traumatic bacterial meningitis were admitted in the Clinic of Infectious Diseases from Iasi between 1, 01, 1990-31, 12, 1994. Head trauma, lumbar punctures and iatrogenic meningitis infections were the causes cerebromeningitis infections. The diagnosis is usually difficult because of the poor specificity of the clinical signs. Predominant pathogens were gram-negative bacteria and Staphylococcus in iatrogenic meningitis and gram-positive bacteria (S. pneumoniae) in traumatic meningitis. The treatment was based on the use penicillin G + chloramphenicol, 3rd generation cephalosporins and sometimes 2nd generation quinolones. Ten of the 87 patients with iatrogenic and traumatic cerebromeningitis infections died (10.3%).
Assuntos
Traumatismos Craniocerebrais/complicações , Meningites Bacterianas/diagnóstico , Complicações Pós-Operatórias/diagnóstico , Antibacterianos , Bactérias/isolamento & purificação , Líquido Cefalorraquidiano/microbiologia , Traumatismos Craniocerebrais/tratamento farmacológico , Quimioterapia Combinada/uso terapêutico , Humanos , Doença Iatrogênica , Meningites Bacterianas/tratamento farmacológico , Meningites Bacterianas/etiologia , Complicações Pós-Operatórias/tratamento farmacológico , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Fatores de TempoAssuntos
Surtos de Doenças/epidemiologia , Meningite Viral/epidemiologia , Estações do Ano , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Meningite Viral/diagnóstico , Meningite Viral/microbiologia , Romênia , População Rural , População UrbanaAssuntos
Infecções por Enterobacteriaceae/diagnóstico , Adolescente , Criança , Pré-Escolar , Terapia Combinada , Diarreia/diagnóstico , Diarreia/etiologia , Diarreia Infantil/diagnóstico , Diarreia Infantil/etiologia , Quimioterapia Combinada , Enterobacter/isolamento & purificação , Infecções por Enterobacteriaceae/microbiologia , Infecções por Enterobacteriaceae/terapia , Feminino , Humanos , Lactente , Recém-Nascido , MasculinoRESUMO
In May 1981 the hand, foot and mouth disease was diagnosed for the first time in Ramaia in a 4 year old child. The onset of the disease was characterized by moderate fever, coryza and spontaneous endobuccal pains followed at a short interval of time by the simultaneous of a papulo-vesicular eruption on hands and feet. The eruption was prevalent on the hands and feet fingers as well as on the palmar and plantar regions. Isolated aphthous lesions were seen on the vestibular mucosa. Morphologically, the intraepidermic site of the lesion with an advanced acantholytic process in the vesicular area was noticed. In the superficial and deep tissue perivascular infiltrate with mononucleares were present.
