[Chemical safety cards as a fundamental information source for chemical exposure]. / Karty Bezpieczenstwa Chemicznego jako podstawowa informacja o zagrozeniu substancjami chemicznymi.

The Polish version of/International Chemical Safety Cards is based on the translation of the International Chemical Safety Card (ICSC) developed within the International Programme on Chemical Safety (IPCS) in cooperation with and financial support of the Commission of the European Communities (CEC). International Chemical Safety Cards comprise basic information and requirements in the field of chemical safety as well as in/health and environment protection during production, transportation and application stages. Cards are a simple and easy available source of information for control services involved in labour hygiene, technical supervision, industrial health services at lower levels as well as for employers and employees. The cards should be available at each work place and at each work-post.

[Effect of superoxide dismutase on the number of chromosome aberrations in lymphocytes after irradiation of human blood preparations]. / Wplyw dysmutazy ponadtlenkowej na wydajnosc aberracji chromosomowych limfocytów po napromieniowaniu preparatów krwi ludzkiej.

The aim of the present study was to determine the radioprotective effects of endo- and exogenous SOD on the number of post-radiation chromosomal aberrations in human lymphocytes from irradiated samples of whole blood. Blood samples from 17 donors were irradiated with the dose of 1 Gy of neutron radiation or with 2 Gy of gamma radiation. Specific endogenous activity of SOD was assessed in lymphocytes from both irradiated and non-irradiated blood samples. Lymphocytes were then cultured in standard conditions with the application of PHA as a stimulator of cell divisions. The rate of chromosomal aberrations was determined in lymphocytes obtained from these cultures. Preliminary results revealed relatively low SOD activity in lymphocytes from normal (non-irradiated) blood samples, though it could vary among individuals from 1.19 to 8.81 U/mg of protein (in extreme cases the differences are even eight-fold). In further experiments, however, no relationship between the level of endogenous SOD activity and number of postradiation chromosomal aberrations was found (exposure of blood samples to the dose of 1 Gy of neutron high LET radiation.

[Superoxide dismutase activity in selected morphotic components of human peripheral blood]. / Aktywnosc enzymatyczna dysmutazy ponadtlenkowej (SOD) wybranych skladników morfotycznych ludzkiej krwi obwodowej.

The peripheral blood of 32 healthy men, aged 20-50 years, constituted material for isolating 4 cell fractions: erythrocytes, lymphocytes, granulocytes, and platelets. The adrenaline method was used to determine SOD enzymatic activity. The results of these estimations for isolated blood cells would indicate their following classification by the progressive activity values: platelets less than granulocytes less than erythrocytes less than lymphocytes. The SOD activity differences for the examined blood cells were statistically significant. Furthermore, it was found that there was a marked correlation (greater than 0.8 probability) between the SOD activity of lymphocytes and platelets, and a correlation with slightly lower probability (greater than 0.7) for erythrocytes and platelets.

[Enzymatic activity of superoxide dismutase in lymphocytes and erythrocytes in people of different ages]. / Aktywnosc enzymatyczna dysmutazy ponadtlenkowej (SOD) limfocytów i erythrocytów u ludzi w róznym wieku.

The studies were aimed at testing whether or not there is a dependence between the enzymatic activity of superoxide dismutase (SOD) in lymphocytes and erythrocytes of peripheral blood, and the age between 20 and 60 years. Examined were 235 healthy men working in leather plants. Between the ages 41 and 50 years SOD enzymatic activity of lymphocytes was found to show a statistically significant decrease. SOD enzymatic activity of erythrocytes does not undergo significant changes during the occupationally active period of life for men (20-60 years). The predominant values of SOD enzymatic activity of lymphocytes were found within 0-1.0 U/10(6) lymphocytes and within 50-200 U/ml blood in case of SOD activity in erythrocytes.