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1.
Ann Hum Biol ; 39(1): 19-27, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22117592

RESUMO

BACKGROUND AND AIM: To identify the distribution and explore the relationship between ACTN3 genotypes and power and body composition phenotypes. SUBJECTS AND METHODS: Case control and association studies were employed using a homogeneous group of players (n = 102) and a control group (n = 110). Power-related phenotypes were measured using the counter movement jump (CMJ) and body composition phenotypes by dual-energy X-ray absorptiometry (DXA). Statistics used were Pearson's chi-square, ANCOVA, coefficients of correlation and independent t-tests. Genotyping was carried out using polymerase chain reaction followed by enzymatic Ddel digestion. RESULTS: Genotype proportions of players were compared with controls (p = 0.07). No significant genotype differences occurred between forwards or backs (p = 0.822) or within-forwards (p = 0.882) or within-backs (p = 0.07). Relative force and velocity were significantly larger in backs, power significantly greater in forwards; in body composition, all phenotypes were significantly greater in forwards than backs. Correlations between phenotypes were greater for the RX genotype (p = 0.05-0.01). CONCLUSIONS: Relationships between ACTN3 genotypes and power or body composition-related phenotypes were not significant. As fat increased, power-related phenotypes decreased. As body composition increased, power-related phenotypes increased.


Assuntos
Actinina/genética , Atletas , Composição Corporal/genética , Futebol Americano , Adolescente , Fenômenos Biomecânicos/genética , Estudos de Casos e Controles , Feminino , Frequência do Gene/genética , Genótipo , Humanos , Masculino , Adulto Jovem
2.
J Sports Med Phys Fitness ; 50(3): 350-5, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20842098

RESUMO

AIM: The present study examined the hypothesis that there were no significant differences between forwards and backs in the elements of leg power between the ID and DD genotypes of the ACE (I/D) gene in developing young adult Rugby Union players. METHODS: Sixty-eight players were recruited to identify the distribution of genotypes between forwards and backs. Fifty-eight players were investigated for leg power. Forwards (n=28) comprised 15 ID and 13 DD genotypes, and backs (n=30) 19 ID and 11 DD genotypes. Leg power was measured on a force platform using a counter movement jump; the parameters of interest were peak and relative force, peak and relative power, displacement and velocity. The three-primer polymerase chain reaction was used to assay the region of interest for I and D variants of the ACE gene. The distribution of genotypes was determined by chi-square and comparisons between forwards and backs made using the independent t-test. RESULTS: No significant differences were identified in the distribution of genotypes between forwards and backs (χ2=2.2, P=0.336). However, significant differences were identified between forwards and backs in a number of components of leg power. Backs had significantly larger values than forwards for relative force (1.50 vs. 1.30 Wt%, P=0.001) and relative power (27.1 vs. 24.3 W.kg-1, P=0.034) for the ID genotype, whereas backs had significantly larger values than forwards for displacement (0.42 vs. 0.38 m, P=0.049) and velocity (2.76 vs. 2.55 m.s.(-1), P=0.007) for the DD genotype. CONCLUSION: The characteristics of leg power identified will enhance the functional requirements of players according to playing position and commitment.


Assuntos
Desempenho Atlético/fisiologia , Futebol Americano/fisiologia , Perna (Membro)/fisiologia , Força Muscular/fisiologia , Peptidil Dipeptidase A/genética , Absorciometria de Fóton , Antropometria , Composição Corporal , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Estudos Transversais , Genótipo , Humanos , Masculino , Adulto Jovem
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