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Introduction A paucity of data exists regarding pregnancy outcome data in women with polycystic ovarian syndrome (PCOS). Therefore, we conducted this study to compare the pregnancy outcomes of women with and without in Indian population. Materials and methods A total of 102 antenatal pregnant women aged between 18 and 45 years were included in this study conducted at the Department of Obstetrics and Gynecology, Pradyumna Bal Memorial Hospital, Kalinga Institute of Medical Sciences, Bhubaneswar, India. Fifty-one women had PCOS, and 51 women served as controls. We recorded patient demographic, clinical, menstrual, and pregnancy data for each group. All participants were monitored until delivery, and we recorded maternal outcomes, including spontaneous abortion, preterm birth, gestational diabetes mellitus (GDM), and pregnancy-induced hypertension (PIH). We used IBM SPSS Statistics version 20.0 for Windows (Armonk, NY: IBM Corp.) for statistical analysis and the chi-square test to analyze relationships in categorical variables. Results Most participants were aged between 20 and 30 years (64.7%). A high body mass index (BMI) was twice as common in women with PCOS than the control group. Most women with PCOS with pregnancy complications were overweight (62.7%) with a BMI of 25 to 29.9 kg/m2. A majority of women in the PCOS group (86.3%) required reproductive technology assistance, while none in the control group needed the same type of assistance. In the PCOS group, spontaneous abortions (SAB) occurred in 5.9%, GDM occurred in 17.6%, PIH in 21.6%, and preterm births in 33.3%. By contrast, the control group saw SAB occur in only 3.9%, GDM occurred in 9.8%, PIH was identical in 21.6%, and preterm births occurred in 17.6% of women without PCOS. Cesarian delivery occurred in 64.7% of women with PCOS, while only 39.2% of women without PCOS had cesarian delivery was statistically not significant. Conclusion We conducted this study to assess the impact of PCOS on pregnancy against pregnant women without PCOS. Pregnant women with PCOS were more likely to experience complications such as SAB, GDM, and preterm birth than pregnant women without PCOS. Therefore, pregnancies in women with PCOS are high-risk pregnancies that require frequent and timely antenatal care.
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Introduction: Placental calcification, identified before the 36th week of gestational age, is known as premature placental calcification (PPC). PPC could be a clue for the poor fetal outcome. However, its association with adverse perinatal outcomes is yet to be confirmed. Objective: The primary objective was to determine and compare the perinatal outcomes in pregnancies with and without documented premature placental calcification. Methodology: The present study was a prospective cohort study performed from October 2017 to September 2019. We consecutively enrolled 494 antenatal women who presented to our antenatal OPD after taking consent to participate in our study. Transabdominal sonographies were conducted between 28-36 weeks of gestation to document placental maturity. We compared maternal and fetal outcomes between those who were identified with grade III placental calcification (n = 140) and those without grade III placental calcification (n = 354). Results: The incidence of preeclampsia, at least one abnormal Doppler index, obstetrics cholestasis, placental abruption, and FGR (fetal growth restriction) pregnancies were significantly higher in the group premature placental calcification. We also found a significantly increased incidence of Low APGAR (Appearance, Pulse, Grimace, Activity, and Respiration) scores, NICU (Neonatal Intensive Care Unit) Admission, Abnormal CTG (cardiotocography), meconium-stained liquor, and low birth weight babies in those with grade III placental calcification. Conclusion: Clinicians should be aware of documenting placental grading while performing ultrasonography during 28 to 36 weeks. Ultrasonographically, the absence of PPC can define a subcategory of low-risk pregnant populations which probably need no referral to specialized centers and can be managed in these settings.
