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J Complement Integr Med ; 9: Article 15, 2012 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-22850071

RESUMO

Typhoid is one of the most serious infectious bacterial diseases in third world countries. It is usually treated by traditional antibiotics but due to the appearance of antibiotic resistant strains physicians opt for phyto products and other alternative medicines for the treatment of typhoid. Baptisia, an extract from indigo plant root, has been proved to be highly effective ultradilute medicine for the treatment of typhoid; however, the mode of action of the ultradilute extract is uncertain. Due to the antigenic variations of Salmonella it seems to induce immuno system by activating both T and B cells by the formation of antibodies. This principle seems to be highly effective for the development of typhoid vaccine. The present studies found that Baptisia administration possibly caused a salmonella-like reaction in the body as this extract produces an endogenous antibody similar to salmonella reaction. Thus, this study suggests that Baptisia tinctoria extract can be used for the prevention and treatment of typhoid.


Assuntos
Antibacterianos/farmacologia , Formação de Anticorpos/efeitos dos fármacos , Fabaceae , Fitoterapia , Extratos Vegetais/farmacologia , Febre Tifoide/tratamento farmacológico , Aglutinação/efeitos dos fármacos , Testes de Aglutinação , Antibacterianos/uso terapêutico , Anticorpos Antibacterianos/metabolismo , Antígenos de Bactérias , Criança , Quimioterapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Extratos Vegetais/uso terapêutico , Raízes de Plantas , Plantas Medicinais , Análise de Componente Principal , Salmonella typhi/efeitos dos fármacos , Salmonella typhi/imunologia , Salmonella typhi/patogenicidade , Febre Tifoide/imunologia , Febre Tifoide/microbiologia , Virulência/efeitos dos fármacos
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