Assuntos
Anormalidades Múltiplas/genética , Anormalidades Múltiplas/patologia , Deformidades Congênitas da Mão/genética , Deformidades Congênitas da Mão/patologia , Perda Auditiva Neurossensorial/genética , Perda Auditiva Neurossensorial/patologia , Deficiência Intelectual/genética , Ceratodermia Palmar e Plantar/genética , Ceratodermia Palmar e Plantar/patologia , Adolescente , Criança , Feminino , Humanos , Masculino , Linhagem , IrmãosRESUMO
Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.
Assuntos
Dermatite/patologia , Dermatopatias Papuloescamosas/patologia , Adulto , Biópsia , Ciproeptadina/uso terapêutico , Dermatite/tratamento farmacológico , Fármacos Dermatológicos/uso terapêutico , Glucocorticoides/uso terapêutico , Antagonistas dos Receptores Histamínicos H1/uso terapêutico , Humanos , Hidrocortisona/análogos & derivados , Hidrocortisona/uso terapêutico , Ceratose/patologia , Linfócitos/patologia , Masculino , Prednisolona/uso terapêutico , Pele/patologia , Dermatopatias Papuloescamosas/tratamento farmacológicoRESUMO
Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.
Assuntos
Síndrome de Ehlers-Danlos/diagnóstico , Síndrome de Ehlers-Danlos/genética , Predisposição Genética para Doença , Adolescente , Seguimentos , Deformidades Congênitas da Mão/diagnóstico , Humanos , Hipogonadismo/diagnóstico , Hipogonadismo/genética , Cifose/diagnóstico , Cifose/genética , Masculino , Medição de Risco , Índice de Gravidade de Doença , IrmãosRESUMO
Cicatricial pemphigoid (CP) occurring in a 60-year-old male is described. He had involvement of conjunctival, nasal and oral mucosae, in addition to skin lesions. Diagnosis was confirmed by histopathology. He responded well to oral steroids and dapsone. However, vision in one eye was lost.
Assuntos
Gelatina , Hemoglobinas , Lactoglobulinas , Sais , Água , Animais , Bovinos , Fenômenos Químicos , QuímicaAssuntos
Eletrólitos , Soroalbumina Bovina , Água , Ligação Proteica , Desnaturação Proteica , TermodinâmicaRESUMO
Data on 30 three-way maize (Zea mays L.) hybrids formed from 5 inbred lines were subjected to the combining ability type of analysis. The relative importance of general and specific line effects in maize three-way hybrids was studied by the Ponnuswamy and Das (1973) method. It was also shown that this analysis provides the breeder with the basic information necessary to choosing proper breeding materials and in deciding the order in which they should be combined to get desirable three-way hybrids.
