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Biomed Khim ; 55(3): 247-54, 2009.
Artigo em Russo | MEDLINE | ID: mdl-19663000

RESUMO

Application of blood plasma metabolites fingerprinting for the diagnostic of the 2nd stage of prostate cancer has been investigated. The diagnostic sensitivity (95%), specificity (96.7%) and accuracy (95.7%) of the metabolic fingerprinting were much higher then those for PSA test (35%, 83.3% and 51.7%, respectively) for the same patients. Area under the ROC-curve (0.994) suggests that the proposed approach is effective and can be used for clinical applications.


Assuntos
Biomarcadores Tumorais/sangue , Proteínas Sanguíneas/análise , Neoplasias da Próstata/sangue , Humanos , Masculino , Metaboloma , Neoplasias da Próstata/diagnóstico , Curva ROC , Espectrometria de Massas por Ionização por Electrospray
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