[Large granular lymphocyte CD3+CD56+ Leukemia revealed by ocular tumor]. / Leucémie à grands lymphocytes granuleux CD3+ CD56+ révélée par une tumeur oculaire.

Large granular lymphocyte leukemia (LGL) constitutes a heterogeneous entity with very different immunophenotypic, clonal and evolutionary characteristics. The most common LGL-T are CD3 +, CD8 +, CD16 +, CD57 +, CD56-. The majority of patients have a chronic disease, systemic signs are rare, and symptoms mainly result from neutropenia or associated autoimmune diseases. We report here a very special case of a 44-year-old woman patient diagnosed with aggressive LGL-T variant also expressing CD56.