[Correction of catecholamine-induced myocardial damage with ionol]. / Korrektsiia ionolom katekholaminovykh povrezhdenii miokarda.

Experiments on male rats exhibiting both high and low resistance to hypoxia have shown that ionol acts as a cardioprotective agent in the adrenalin-induced myocardial dystrophy. This effect is realized through the depression of the lipid peroxidation activity.

[Effect of prostaglandin E2 on the development of myocardial damage in rats with various resistance to hypoxia]. / Vliianie prostaglandina E2 na razvitie adrenalinovogo povrezhdeniia miokarda u krys s razlichnoi ustoichivost'iu k gipoksii.

Experiments conducted on male rats with congenital high and low resistance to hypoxia (HH and LH, respectively) have revealed, that injection of prostaglandin E2 (PHE2) 15 min before the injection of adrenalin essentially decreases the activity of lipid peroxidation in myocardium as compared with animals which have been injected to only adrenalin. This modulative effect (PHE2) on the action of adrenalin was more pronounced in LH-rats. Consequently, the activity of the prostaglandin stress-limiting system determines to a great extent the organism resistance to hypoxia.