1.
Bioorg Med Chem Lett
; 22(12): 4173-8, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22583618
RESUMO
Small peptidic kappa agonists were covalently linked to the reactive lysine of the CovX antibody to create compounds having potent activity at the kappa receptor with greatly extended half-life when compared to the parent peptide as exemplified by compound 20.