[Free-radical oxidation, the glutathione system and the status of the gastric mucosa in peptic ulcer in adolescents and young people under dynamic restorative treatment]. / Vil'noradykal'ne okyslennia, systema hlutationu ta stan slyzovoï obolonky shlunka pry vyrazkovii khvorobi u khvorykh pidlitkovoho ta iunats'koho viku v dynamitsi vidnovnoho likuvannia.

1.5-2 versus 3-4 months following the in-patient stage of treatment without further antiradical therapy, patients-juveniles and young people with ulcer disease demonstrate compensated versus decompensated disorders in the glutathione system activity respectively, which results in disturbances in the free-radical oxidation processes, amplification of alteration, decrease in proliferation in the mucous membrane of the stomach. Antiradical therapy being continued avoids such a pathology. A necessity is substantiated for taking measures on an uninterrupted long-term basis, aimed to correct the free-radical oxidation processes in patients with peptic ulcer of juvenile age and young people.

[The cytotoxic action of metal stearates and its correlation with the toxicity for animals]. / Tsitotoksicheskoe deistvie stearatov metallov i ego korreliatsiia s toksichnost'iu dlia zhivotnykh.

Toxic effects of lead, cadmium, barium, silver, zinc and calcium stearates on the Rh-type cells culture have been revealed. The expressiveness of the cytotoxic action correlated with the toxicity degree for laboratory animals. The strongest (r = 0,98; p less than 0,01) was the correlation between cytotoxicity parameter (the minimal cytoclastic concentration) and the inhalation toxicity parameter in animals (lim(ac)). The results permitted deriving formulae for predicting some toxicity parameters (intraperitoneal LD50, lim(ac)), hygienic regulations (MAC), and showed that the prediction based on cytotoxicity data is more reliable, than that based on toxicometric parameters in short-term experiments used for such purpose.