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1.
J Technol Behav Sci ; 3(4): 294-300, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30547080

RESUMO

Recent findings show teenagers use social media increasingly in their daily life. There is also a consensus that social media have both pros and perils on students' academic affairs. The objective of this study is to assess how Ethiopian secondary school students perceive the benefits and risks associated with social media use. Data were collected from 353 secondary schools students through self-reported questionnaire. The findings reveal that the leading perceived benefits of social media are recreational and relational purposes. The role social media play in students' academic activities is likely less considered. As a pilot study in a developing country, this study may raise awareness of schools, teachers, and parents about the benefits and risks of using social media for teenager students. Thereby, there will be future researches that enable them to effectively monitor their students to use social media primarily for academic purposes.

2.
BMC Complement Altern Med ; 15: 187, 2015 Jun 18.
Artigo em Inglês | MEDLINE | ID: mdl-26084371

RESUMO

BACKGROUND: Embelia schimperi has been used for the treatment of intestinal parasites especially tapeworm infestations for centuries in Ethiopia. However, there is lack of scientific based evidences regarding the efficacy, safety and phytochemical analysis of this plant despite its frequent use as an anthelmintic. This study has therefore evaluated the efficacy and acute toxicity of E. schimperi thereby generating relevant preclinical information. METHODS: The anthelmintic activities of the crude hydroalcoholic extract of E. schimperi and the isolated compound, embelin, were conducted using in vivo and in vitro models against the dwarf tapeworm, Hymenolepis nana, and the hookworm, Necator americanus, respectively. LD50 of the crude hydroalcoholic extract was determined using Swiss albino mice following the OECD guidelines. Chemical characterization of the isolated embelin was conducted using UV-spectroscopy, HPLC and NMR. RESULTS: In the acute toxicity study no prominent signs of toxicity and mortality were recorded among the experimental animals at the highest administered dose. Hence the LD50 of the plant was found to be higher than 5000 mg/kg. In vivo cestocidal activity of the crude hydroalcoholic extract of E. schimperi showed 100% parasite clearance at 1000 mg/kg, while the diammonium salt of embelin showed 85.3% parasite clearance at 750 mg/kg. The in vitro anthelminthic activity study revealed that the LC50 value of the crude extract and albendazole were 228.7 and 51.33 µg/mL, respectively. CONCLUSION: The results clearly indicated that the hydroalcoholic extract of E. schimperi and the diammonium salt of the isolated compound embelin had anthelmintic activity against hookworm larva in vitro and H. nana in vivo. Hence the findings of this study showed Embelia schimperi appears to possess some anthelmintic activity that may support the usage of these plants by local traditional healers to treat helminthic infestations.


Assuntos
Anti-Helmínticos , Embelia/química , Extratos Vegetais , Plantas Medicinais/química , Animais , Anti-Helmínticos/química , Anti-Helmínticos/farmacologia , Etiópia , Himenolepíase/parasitologia , Hymenolepis nana/efeitos dos fármacos , Camundongos , Extratos Vegetais/química , Extratos Vegetais/farmacologia
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