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1.
Sci Rep ; 10(1): 14024, 2020 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-32820204

RESUMO

Debris flows can grow greatly in size and hazardous potential by eroding bed and bank material, but effective hazard assessment and mitigation is currently hampered by limited understanding of erosion and deposition dynamics. We have collected high-resolution pre- and post-flow topography for 6 debris flows over a 3 km long unconsolidated reach of the Illgraben channel in the Swiss Alps with drone-based photogrammetry. We show that the spatio-temporal patterns of erosion and deposition in debris-flow torrents are highly variable and dynamic. Check dams strongly control the spatial patterns of erosion and deposition. We identify a memory effect where erosion is strong at locations of strong deposition during previous flows and vice versa. Large sediment inputs from subcatchments initially result in new channel erosion through the subcatchment deposits and simultaneous upstream deposition, likely as a result of backwater effects. It is generally believed that erosion increases with debris-flow magnitude, but we show that there is a limit to debris-flow bulking set by channel geometry. These findings provide key guidelines for flow volume forecasting, emphasizing the importance of memory effects and the need to resolve both erosion and deposition in predictive models.

2.
J Geophys Res Planets ; 124(8): 2246-2271, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31763111

RESUMO

Understanding the initial and flow conditions of contemporary flows in Martian gullies, generally believed to be triggered and fluidized by CO2 sublimation, is crucial for deciphering climate conditions needed to trigger and sustain them. We employ the RAMMS (RApid Mass Movement Simulation) debris flow and avalanche model to back calculate initial and flow conditions of recent flows in three gullies in Hale crater. We infer minimum release depths of 1.0-1.5 m and initial release volumes of 100-200 m3. Entrainment leads to final flow volumes that are ∼2.5-5.5 times larger than initially released, and entrainment is found necessary to match the observed flow deposits. Simulated mean cross-channel flow velocities decrease from 3-4 m/s to ∼1 m/s from release area to flow terminus, while flow depths generally decrease from 0.5-1 to 0.1-0.2 m. The mean cross-channel erosion depth and deposition thicknesses are ∼0.1-0.3 m. Back-calculated dry-Coulomb friction ranges from 0.1 to 0.25 and viscous-turbulent friction between 100 and 200 m/s2, which are values similar to those of granular debris flows on Earth. These results suggest that recent flows in gullies are fluidized to a similar degree as are granular debris flows on Earth. Using a novel model for mass flow fluidization by CO2 sublimation we are able to show that under Martian atmospheric conditions very small volumetric fractions of CO2 of ≪1% within mass flows may indeed yield sufficiently large gas fluxes to cause fluidization and enhance flow mobility.

3.
Phys Rev Lett ; 116(23): 235101, 2016 Jun 10.
Artigo em Inglês | MEDLINE | ID: mdl-27341240

RESUMO

The dynamics of magnetic reconnection is investigated in a laboratory experiment consisting of two magnetic flux ropes, with currents slightly above the threshold for the kink instability. The evolution features periodic bursts of magnetic reconnection. To diagnose this complex evolution, volumetric three-dimensional data were acquired for both the magnetic and electric fields, allowing key field-line mapping quantities to be directly evaluated for the first time with experimental data. The ropes interact by rotating about each other and periodically bouncing at the kink frequency. During each reconnection event, the formation of a quasiseparatrix layer (QSL) is observed in the magnetic field between the flux ropes. Furthermore, a clear correlation is demonstrated between the quasiseparatrix layer and enhanced values of the quasipotential computed by integrating the parallel electric field along magnetic field lines. These results provide clear evidence that field lines passing through the quasiseparatrix layer are undergoing reconnection and give a direct measure of the nonlinear reconnection rate. The measurements suggest that the parallel electric field within the QSL is supported predominantly by electron pressure; however, resistivity may play a role.

4.
Nat Commun ; 6: 7543, 2015 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-26102485

RESUMO

Liquid water is currently extremely rare on Mars, but was more abundant during periods of high obliquity in the last few millions of years. This is testified by the widespread occurrence of mid-latitude gullies: small catchment-fan systems. However, there are no direct estimates of the amount and frequency of liquid water generation during these periods. Here we determine debris-flow size, frequency and associated water volumes in Istok crater, and show that debris flows occurred at Earth-like frequencies during high-obliquity periods in the last million years on Mars. Results further imply that local accumulations of snow/ice within gullies were much more voluminous than currently predicted; melting must have yielded centimetres of liquid water in catchments; and recent aqueous activity in some mid-latitude craters was much more frequent than previously anticipated.

5.
Clin Neuropathol ; 26(3): 93-110, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-19157001

RESUMO

Medulloblastoma is a malignant, invasive embryonal tumor of the cerebellum with preferential manifestation in children, predominantly neuronal differentiation and an inherent tendency to metastasize via CSF pathways. In this review we present an overview of the clinicopathological aspects of medulloblastoma and the recent developments in the biology and genetics of these embryonal brain tumors. Increased knowledge of the signaling pathways that play a role in normal cerebellum development and tumor formation may lead to new therapeutic approaches resulting in a higher cure rate and a better quality of life of medulloblastoma patients.


Assuntos
Neoplasias Cerebelares/patologia , Meduloblastoma/patologia , Animais , Neoplasias Cerebelares/genética , Neoplasias Cerebelares/terapia , Humanos , Meduloblastoma/genética , Meduloblastoma/terapia , Transdução de Sinais
6.
Ned Tijdschr Geneeskd ; 144(4): 174-8, 2000 Jan 22.
Artigo em Holandês | MEDLINE | ID: mdl-10668544

RESUMO

Three previously healthy children, two girls aged 2 and almost 5 years and a boy aged 20 months, developed a progressively stumbling gait within days. In two this occurred after a period of weeks during which they complained of, or seemed to have back pain. In all three cases acute spinal cord compression by a malignant tumour was diagnosed. Histological examination revealed Ewing sarcoma, granulocytic sarcoma and T-cell lymphoma. Surgical decompression led to complete neurological recovery. Although rare, acute spinal cord compression during childhood is a medical emergency because of the risk of neurological morbidity. Back pain, weakness and a stumbling gait usually are the first symptoms. Sensory symptoms and sphincter dysfunction may develop later. Early recognition is essential, as prognosis depends on neurological findings and duration of symptoms when treatment is started.


Assuntos
Apraxia da Marcha/etiologia , Compressão da Medula Espinal/complicações , Neoplasias da Coluna Vertebral/complicações , Neoplasias da Coluna Vertebral/diagnóstico , Doença Aguda , Dor nas Costas/etiologia , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Leucemia Mieloide/complicações , Leucemia Mieloide/diagnóstico , Linfoma de Células T/complicações , Linfoma de Células T/diagnóstico , Transtornos Linfoproliferativos/complicações , Transtornos Linfoproliferativos/diagnóstico , Masculino , Sarcoma de Ewing/complicações , Sarcoma de Ewing/diagnóstico , Compressão da Medula Espinal/etiologia , Compressão da Medula Espinal/terapia , Neoplasias da Coluna Vertebral/terapia
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