RESUMO
A 26-year-old woman underwent operative hysteroscopy to remove a polypoid lesion, responsible for recurrent abnormal uterine bleeding. The polypoid mass was 4 cm long, smooth, with dilated vessels. It had a large base and originated from the fundum and posterior wall of the uterus. Pathological examination of the resected specimen showed low-grade stromal sarcoma. The patient subsequently underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy. No tumor residual was found in the surgical specimen. As diagnosis of stromal sarcoma is too difficult to be made preoperatively, the complete resection of all intracavitary lesions and the pathology of all tissue specimens are suggested.
Assuntos
Neoplasias do Endométrio/patologia , Neoplasias do Endométrio/cirurgia , Sarcoma do Estroma Endometrial/patologia , Sarcoma do Estroma Endometrial/cirurgia , Adulto , Técnicas de Diagnóstico por Cirurgia , Tubas Uterinas/cirurgia , Feminino , Humanos , Histerectomia , Histeroscopia , Ovariectomia , ReoperaçãoRESUMO
Retroperitoneal liposarcoma is a rare malignancy. We report a case of retroperitoneal myxoid liposarcoma in pregnancy. The patient died of the disease eight months after surgery.
Assuntos
Lipossarcoma/diagnóstico , Complicações Neoplásicas na Gravidez/diagnóstico , Neoplasias Retroperitoneais/diagnóstico , Adulto , Diagnóstico Diferencial , Feminino , Humanos , GravidezRESUMO
TNF-alpha levels in sera from patients with gynecological cancers were evaluated by ELISA and compared with those of patients with benign ovarian cysts or of anonymous healthy donors. Patients with cervical and endometrial carcinoma and with benign ovarian cysts showed levels of TNF-alpha similar to those of healthy donors. In contrast, significantly increased levels of TNF-alpha were found in patients with ovarian carcinoma, regardless of the stage of disease.
Assuntos
Biomarcadores Tumorais/sangue , Neoplasias dos Genitais Femininos/sangue , Fator de Necrose Tumoral alfa/análise , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Estadiamento de Neoplasias , Cistos Ovarianos/sangue , Neoplasias Ovarianas/sangue , Neoplasias Ovarianas/patologia , Valores de Referência , Neoplasias do Colo do Útero/sangue , Neoplasias Uterinas/sangueRESUMO
PIP: 3 women (an 18 year old, a 33 year old, and a 39 year old) were admitted to the University of Bologna's hospital, each reporting abdominal cramping and 2 complained of vaginal bleeding and lypothymia. 2 women had an IUD and had a previous appendectomy, the other woman had a previous abortion, and all reported amenorrhea. Pelvic ultrasound helped establish the diagnosis of an ovarian pregnancy (OP), but diagnosis was confirmed using a laparotomy. A surgeon consequently performed a salpingo-oophorectomy on each woman. The researchers noted an OP incidence of 1.6% of all ectopic pregnancies in their study. All 3 cases fit the pathologic criteria for OP: 1.) normal and distinct tube; 2.) a gestational sac in the normal location of the ovary; 3.) connection of the gestational sac to the uterus by the utero-ovarian ligament; and 4.) ovarian tissue within the walls of the sac. 1 patient even had an implanted fertilized ovum which grew within the graafian follicle, and a corpus luteum was within the wall of the gestational sac. OP generally happens in women who have an IUD and/or a history of pelvic inflammatory disease, such as an appendectomy. Both risk factors may alter normal ovary functions, and OP may result from either a disorder in the release of the ovum or a delay in ovulation.^ieng
