[Initial study of an experimental model for bladder augmentation]. / Estudio inicial de un modelo experimental para la ampliación vesical.

Since Coffey described in 1910 the Uretero-sigmoidostomy, the first auto-continent urinary derivation, many techniques have been developed and used for bladder augmentation, although none of them has been considered fully satisfactory. The availability of a product made of a bovine collagen and glycosaminoglycan base, used for regenerating dermis and oral mucosa induced us to start this study on rabbit bladder in order to verify if muscular fibers might grow in its interior. For that purpose we used 6 New Zealand rabbits, to which we implanted a fragment of artificial dermis inside the detrusor after dissecting it. We present our results after 3 and 6 weeks postoperatively.

Estudio inicial de un modelo experimental para la ampliación vesical / Initial study of an experimental model for bladder augmentation

Desde la descripción de Coffey en 1910 de la uretero-sigmoidostomía, primera derivación urinaria continente, se han utilizado multitud de técnicas para ampliar la vejiga, pero ninguna plenamente satisfactoria. La aparición de un producto compuesto por una matriz de colágeno bovino y glicosaminoglicano, utilizado en regeneración de dermis y mucosa oral, nos indujo a realizar este estudio sobre vejiga de conejo con el fin de comprobar si podrían crecer fibras musculares en su interior. Para ello utilizamos 6 conejos New Zealand, a los que tras dislacerar una porción de detrusor les implantamos un fragmento de dermis artificial. Posteriormente, se realizó estudio anatomopatológico a las tres yseis semanas, con los resultados que posteriormente se detallan (AU)

Since Coffey described in 1910 the Uretero-sigmoidostomy, the first auto-continent urinary derivation, many techniques have been developed and used for bladder augmentation, although none of them has been considered fully satisfactory. The availability of a product made of a bovine collagen and glycosaminoglycan base, used for regenerating dermis and oral mucosa induced us to start this study on rabbit bladder in order to verify if muscular fibers might grow in its interior. For that purpose we used 6 New Zealand rabbits, to which we implanted a fragment of artificial dermis inside the detrusor after dissecting it. We present our results after 3 and 6 weeks postoperatively (AU)