Musculoskeletal disorders and work-related musculoskeletal diseases among nursery school teachers: analysis in a sample in the city of Venice.

SUMMARY: Objectives. Musculoskeletal disorders (MSD) represent one of the most relevant occupational problems. School teachers and particularly nursery school teachers (NST) are reported to have a high prevalence of MSD. We aimed to estimate frequency of MSD in a sample of NST and to bring out cases of work-related musculoskeletal disorders (WRMSD) among these workers. Design. Cross-sectional prevalence study. Setting and participants. NST applying to the trade union patronage between December 2015 and December 2017 for problems of absence from work for health reasons have been proposed the compilation of the Italian version of the Nordic Questionnaire for musculoskeletal disorders. NST who reported MSD underwent medical examination performed by an occupational physician. In accordance with current legislation, certification of occupational disease was completed when a plausible occupational origin of the pathology could be identified. Main outcome measures. MSD and WRMSD prevalence. Results. Questionnaires were completed by 82 NST: 75 (91.5% of the sample) reported at least one MSD. 71 NST underwent medical examination. In 32 subjects (39% of the sample) a diagnosis of musculoskeletal pathology was formulated. Based on work history, 20 cases of probable occupational pathology were reported. Occupational etiology was ascertained for 12 subjects (14.6%): 11 cases of lumbar discopathy / lumbar disc herniation and 1 case of both lumbar disc herniation and tendinopathy of shoulder rotator cuff. Conclusion. Prevalence of musculoskeletal disorders was high and the most frequently affected body sites were similar to those reported in the literature, confirming NST as a group at risk for developing both MSD and WRMSD. Results indicate the importance of taking primary and secondary prevention actions to protect the health of NST.

Machinery-related deaths: relevance of workplace investigation and antemortem radiological data in reconstructing the fatality.

Machinery-related fatalities are one of the leading causes of traumatic occupational deaths. In our report, we present the case of a 40-year-old male who suffered a severe head trauma while working in a cut-foam industry and died despite an early craniectomy. The radiological reconstruction of the skull based on preoperative computed tomography scans disclosed a large depressed conical fracture of the left parietal bone. The 3D-reconstruction of the work area, combined with a fit-matching analysis between the machinery and the depressed skull fracture allowed us to conclude that the head was crushed between the sliding bar of the cutting device and the metallic protuberance on the opposite side. The case underlines the importance of a detailed workplace investigation and of a thorough evaluation of all circumstantial, clinical, radiological, and autopsy data in the reconstruction of machinery-related fatalities to identify any possible legal responsibilities of the worker and/or the employer.

Bone mineral density improvement after successful parathyroidectomy in pre- and postmenopausal women with primary hyperparathyroidism: a prospective study.

The aim of this study was to evaluate the short-term (1 year) changes of the lumbar spine (L2-L4) bone mineral density (LS-BMD) after parathyroidectomy (PTx) in pre- and postmenopausal women with primary hyperparathyroidism (PHPT). A series of 48 women (median age 56 years, range 23-82 years) with confirmed PHPT were prospectively enrolled in the study. Patients who received both oral contraceptives less than 2 years before the diagnosis and estrogen replacement therapy have previously been excluded. All patients underwent LS-BMD by dual energy x-ray absorptiometry before surgery. Patients were divided into two groups: group A (n = 12) premenopausal, and group B (n = 36) postmenopausal patients. The LS-BMD was repeated 12 months after successful PTx. Basal LS-BMD (0.852 +/- 0.061 vs. 0.748 +/- 0.142 g/cm(2)), serum calcium (2.95 +/- 0.23 vs. 2.94 +/- 0.26 mmol/L), creatinine (69.2 +/- 17.5 vs. 82.0 +/- 24.2 micromol/L), alkaline phosphatase (107.4 +/- 43.6 vs. 151.3 +/- 95.7 U/L), osteocalcin (28.6 +/- 9.3 vs. 28.2 +/- 8.3 microg/L), and PTH (192.7 +/- 133.2 vs. 175.2 +/- 132.1 ng/L) levels did not differ significantly (P = NS) between groups. The 1-year LS-BMD was 0.921 +/- 0.048 and 0.825 +/- 0.151 g/cm(2) in group A and B, respectively. In group B patients, the 1-year LS-BMD value did not improve significantly (P = NS), while in group A patients the difference between basal and postsurgical LS-BMD was significant (P < 0.01). In conclusion, PTx should be considered for all patients with PHPT and loss of bone density, but in premenopausal patients a greatest improvement of BMD may be found, suggesting the need of endogenous estrogens in complete lumbar bone recovery after surgery.

Intima-media thickness measurement of the carotid artery in patients with primary hyperparathyroidism. A prospective case-control study and long-term follow-up.

BACKGROUND: The intima-media thickness (IMT) measurement of the common carotid artery is recognized as a reliable marker of systemic atherosclerosis and may be useful in predicting the likelihood of cardiovascular events, since it is related to the extent and severity of coronary artery disease. The aims of this study were to analyze whether correlations exist between the IMT of the common carotid artery and the main clinical and biochemical parameters in patients with primary hyperparathyroidism (PHPT), and to evaluate the possible improvement of the IMT values following parathyroidectomy at long-term follow-up. PATIENTS AND METHODS: Twenty-seven patients (5 men, 22 women; median age 59 years, range 36-82 years) with biochemically confirmed PHPT (Group A, cases), and 27 gender- and age-matched healthy volunteers (Group B, controls) were prospectively enrolled in the study. All patients underwent ultrasound examination and the IMT of each carotid artery were recorded, averaging all values. The measurements were repeated 18-22 months (median 20) later in all patients. RESULTS: A significant (p < 0.05) correlation between age and both systolic BP and IMT, and between IMT and fasting glycaemia was found in each Group. There was an inverse relationship between IMT and serum parathyroid hormone (R = -0.56, p < 0.01), but no correlation (p=NS) was found between IMT and serum calcium (R = -0.14) or serum phosphate (R = 0.07). At follow-up a slight (10.4%) improvement in the mean IMT was observed among Group A patients (0.86 +/- 0.18 vs. 0.77 +/- 0.24; p = 0.12), but the difference was not significant. CONCLUSION: At long term follow-up, the IMT values did not improve significantly and no correlation was found between serum calcium and IMT. These results suggest that hypercalcemia does not represent a reliable risk of carotid atherosclerosis in patients with PHPT.