[Drugs and brief losses of consciousness in the elderly. Results of a case-control multicenter study]. / Médicaments et pertes brèves de connaissance chez les personnes âgées. Résultats d'une étude multicentrique cas contrôle. Le groupe Médicaments et PCB.

To study the possible role of drugs intake in syncope in elderly patients, we conducted a multicentric case-control study in 588 cases and 1818 controls, controlling as an essential confounding variable the underlying cardiovascular diseases. The following class were in excess among the case: non tricyclic antidepressants (p < 0.0001, RR: 4.5), neuroleptic drugs (p < 0.05, RR: 1.8), and antiparkinsonian drugs (p < 0.02, RR: 2.7).