RESUMO
A comparative evaluation of vaccination methods with glycoproteins for the induction of immune responses and protection of the pig against Aujeszky's disease virus (ADV) was performed. Different vaccination routes (intradermal (i.d.) versus intramuscular (i.m.)), inoculation sites (the neck versus the back) and number of inoculation points (2 versus 6) per site were compared. Body weight (BW) changes and viral excretion after challenge were compared with virus-neutralizing titers, antigen-specific IgG and IgA responses in serum and virus-specific lymphoproliferative responses in peripheral blood during the immunisation period. According to BW changes better protection was obtained with six-point than two-point i.d. injections. i.d. vaccination in the back at six points gave similar results as i.m. vaccination in the neck but appeared inferior in the reduction of virus excretion. Regarding the immunological parameters, the virus-specific IgA response in serum gave the best indication for protection. It can be concluded that according to BW changes, six-point i.d. immunisation in the back and i.m. immunisation in the neck provided the best protection and that six-point i.d. injections resulted in a better vaccination than two-point i.d. injections.
Assuntos
Herpesvirus Suídeo 1/imunologia , Pseudorraiva/imunologia , Proteínas do Envelope Viral/imunologia , Vacinas Virais , Animais , Anticorpos Antivirais/sangue , Formação de Anticorpos , Peso Corporal , Ensaio de Imunoadsorção Enzimática , Herpesvirus Suídeo 1/isolamento & purificação , Ativação Linfocitária , Pseudorraiva/prevenção & controle , Vacinas contra Pseudorraiva , Suínos , Vacinação/métodos , Vacinação/veterinária , Proteínas do Envelope Viral/administração & dosagem , Vacinas Virais/administração & dosagem , Eliminação de Partículas ViraisRESUMO
Computerised tomography, used as a diagnostic tool for atrophic rhinitis in pigs, facilitated the macroscopic grading of the nasal structures in live pigs of any age. The results of sequential scans in normal and affected pigs are described; transient atrophy of the ventral conchae was observed in one pig.
Assuntos
Rinite Atrófica/veterinária , Doenças dos Suínos/diagnóstico por imagem , Tomografia Computadorizada por Raios X/veterinária , Animais , Nariz/patologia , Rinite Atrófica/diagnóstico por imagem , SuínosAssuntos
Halotano , Estresse Fisiológico/veterinária , Doenças dos Suínos/diagnóstico , Suínos/genética , Animais , Cruzamentos Genéticos , Suscetibilidade a Doenças , Tolerância a Medicamentos , Feminino , Masculino , Carne/análise , Estresse Fisiológico/diagnóstico , Estresse Fisiológico/genética , Doenças dos Suínos/genéticaRESUMO
A severe outbreak of Trichuris suis infection in piglets is described. Fifteen per cent of the animals died and the morbidity, characterised by weight loss and diarrhoea, was over 50 per cent. The severity of symptoms observed in naturally infected pigs was related to the number of whipworms. A chemotherapeutic trial was worked out with flubendazole mixed in food for naturally infected and artificially infected piglets. Flubendazole at 30 ppm for five consecutive days controlled the infection in the pigs. Immature T suis in artificially infected pigs were also controlled at the same dose administered for 10 consecutive days.
