RESUMO
We report the clinico-pathologic characteristics of 13 cases of Laugier-Hunziker disease, consisting of the presence of oral melanotic macules associated or not to longitudinal nail pigmentation. The presence of regular acanthosis, basal pigmentation without increase in the number of melanocytes and the presence of melanophages in subepidermal connective tissue have been the most constant histopathological characteristics. The term "essential cutaneo-mucous hyperpigmentation" as synonym of Laugier-Hunziker disease is proposed.
Assuntos
Melanose/patologia , Doenças da Boca/patologia , Doenças da Unha/patologia , Transtornos da Pigmentação/patologia , Adolescente , Adulto , Idoso , Tecido Conjuntivo/patologia , Epiderme/patologia , Feminino , Humanos , Masculino , Melanócitos/patologia , Pessoa de Meia-Idade , SíndromeAssuntos
Hérnia Inguinal/patologia , Síndrome de Resistência a Andrógenos/patologia , Síndrome de Resistência a Andrógenos/cirurgia , Biópsia , Doença Crônica , Criptorquidismo/patologia , Criptorquidismo/cirurgia , Diagnóstico Diferencial , Feminino , Hérnia Inguinal/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Orquiectomia , Reoperação , Testículo/patologiaRESUMO
A case of chronic angular cheilitis is reported. Candida albicans was isolated repeatedly and the process developed into epitheliomatous carcinoma. The etiopathogenic role of Candida albicans and possible mechanism of action are discussed.
Assuntos
Candida albicans/isolamento & purificação , Carcinoma de Células Escamosas/diagnóstico , Queilite/microbiologia , Idoso , Doença Crônica , Humanos , MasculinoAssuntos
Neoplasias da Mama/patologia , Carcinoma/patologia , Adulto , Carcinoma/metabolismo , Feminino , HumanosRESUMO
Maria Jose's Sister's lump (metastatic umbilical carcinoma) is a metastasis of more than one malignant tumor (frequently abdominal), but on occasions it is the first sign of disease. A case of a female patient diagnosed as having "umbilical hernia" with peritoneal carcinomatosis, liver metastasis and "frozen pelvis", who died 6 months later, is presented, demonstrating the bad prognosis of this sign.
Assuntos
Neoplasias Abdominais/diagnóstico , Neoplasias Abdominais/secundário , Umbigo/patologia , Idoso , Feminino , HumanosRESUMO
We present a case report of Caroli's disease with related cholangiocarcinoma in a 30 years old white woman. The risk of Caroli's disease malignization is estimated about 7-12% being cholangiocarcinoma the histopathologic pattern most frequently found. This frequency, which is over 100 times higher than that expected in the general population, make us think over the possibility of being some premalignant agent, if not a really carcinogenic one in Caroli's disease. The risk of degeneration is proportional to time of evolution of the disease so, when it is possible, the resective surgery should be elected.
Assuntos
Adenoma de Ducto Biliar/etiologia , Doenças dos Ductos Biliares/complicações , Neoplasias dos Ductos Biliares/etiologia , Ductos Biliares Intra-Hepáticos/anormalidades , Adenoma de Ducto Biliar/diagnóstico , Adenoma de Ducto Biliar/patologia , Adulto , Doenças dos Ductos Biliares/congênito , Doenças dos Ductos Biliares/diagnóstico , Doenças dos Ductos Biliares/patologia , Neoplasias dos Ductos Biliares/diagnóstico , Neoplasias dos Ductos Biliares/patologia , Ductos Biliares Intra-Hepáticos/patologia , Dilatação Patológica/complicações , Dilatação Patológica/congênito , Dilatação Patológica/diagnóstico , Dilatação Patológica/patologia , Feminino , Humanos , SíndromeRESUMO
One hundred and seventy cases of nasal and/or sinus polyps diagnosed in the Pathology Service of the Hospital Militar Central GOMEZ/ULLA of Madrid (Spain) between 1.9.79 and 1.9.88 are reviewed. In two cases areas of 'carcinoma in situ' in the epithelium covering the polyps were demonstrated. The literature is reviewed for reports of malignant transformation and dysplastic changes in nasal and sinusal polyps. We suggest that precancerous changes may occasionally be noted in inflammatory lesions, a fact that pathologists should keep in mind.
