1.
Org Lett
; 11(4): 835-8, 2009 Feb 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19152262
RESUMO
Alpha-branched amides are prepared by multicomponent reactions in which nitriles undergo hydrozirconation to form metalloimines that react with acyl chlorides. The resulting acylimines react with a variety of pi-nucleophiles in the presence of Lewis acids to form the desired amides.