[Ripening of the cervix and induction of labor at term with prostaglandin F2 alpha gel in increasing doses]. / Mûrissement cervical et induction du travail à terme par le gel de prostaglandine F2 alpha à dose croissante.

The induction of labour at term has a place of choice amongst the numerous obstetric applications of prostaglandins. The present clinical trial (50 cases) showed that F2 alpha prostaglandin, after incorporation in a high-viscosity gel and following insertion into the extra-amniotic space, is capable of accelerating cervical ripening and of inducing myometrial activity close to spontaneous physiological conditions. The use of increasing doses of prostaglandin avoids the development of acute foetal distress. Our experience confirmed the efficacy (8% true failures), the rapidity and the good maternal and foetal tolerance of the induction of labour at term by prostaglandins.