Physiological responses to cold exposure in men: a disabled submarine study.

A disabled submarine (DISSUB) lacking power and/or environmental control will become cold, and the ambient air may become hypercapnic and hypoxic. This study examined if the combination of hypoxia, hypercapnia, and cold exposure would adversely affect thermoregulatory responses to acute cold exposure in survivors awaiting rescue. Seven male submariners (33 +/- 6 yrs) completed a series of cold-air tests (CAT) that consisted of 20-min at T(air) = 22 degrees C, followed by a linear decline (1 degrees C x min(-1)) in T(air) to 12 degrees C, which was then held constant for an additional 150-min. CAT were performed under normoxic, normocapnic conditions (D0), acute hypoxia (D1, 16.75% O2), after 4 days of chronic hypoxia, hypercapnia and cold (D5, 16.75% O2, 2.5% CO2, 4 degrees C), and hypoxia-only again (D8, 16.75% O2). The deltaTsk during CAT was larger (P < 0.05) on D0 (-5.2 degrees C), vs. D1 (-4.8 degrees C), D5 (-4.5 degrees C), and D8 (-4.4 degrees C). The change (relative to 0-min) in metabolic heat production (deltaM) at 20-min of CAT was lower (P < 0.05) on D1, D5, and D8, vs. D0, with no differences between D1, D5 and D8. DeltaM was not different among trials at any time point after 20-min. The mean body temperature threshold for the onset of shivering was lower on D1 (35.08 degrees C), D5 (34.85 degrees C), and D8 (34.69 degrees C), compared to D0 (36.01 degrees C). Changes in heat storage did not differ among trials and rectal temperature was not different in D0 vs. D1, D5, and D8. Thus, mild hypoxia (16.75% F1O2) impairs vasoconstrictor and initial shivering responses, but the addition of elevated F1CO2 and cold had no further effect. These thermoregulatory effector changes do not increase the risk for hypothermia in DISSUB survivors who are adequately clothed.

Thermoregulation during cold exposure after several days of exhaustive exercise.

This study examined the hypothesis that several days of exhaustive exercise would impair thermoregulatory effector responses to cold exposure, leading to an accentuated core temperature reduction compared with exposure of the same individual to cold in a rested condition. Thirteen men (10 experimental and 3 control) performed a cold-wet walk (CW) for up to 6 h (6 rest-work cycles, each 1 h in duration) in 5 degrees C air on three occasions. One cycle of CW consisted of 10 min of standing in the rain (5.4 cm/h) followed by 45 min of walking (1.34 m/s, 5.4 m/s wind). Clothing was water saturated at the start of each walking period (0.75 clo vs. 1.1 clo when dry). The initial CW trial (day 0) was performed (afternoon) with subjects rested before initiation of exercise-cold exposure. During the next 7 days, exhaustive exercise (aerobic, anaerobic, resistive) was performed for 4 h each morning. Two subsequent CW trials were performed on the afternoon of days 3 and 7, approximately 2.5 h after cessation of fatiguing exercise. For controls, no exhaustive exercise was performed on any day. Thermoregulatory responses and body temperature during CW were not different on days 0, 3, and 7 in the controls. In the experimental group, mean skin temperature was higher (P < 0.05) during CW on days 3 and 7 than on day 0. Rectal temperature was lower (P < 0.05) and the change in rectal temperature was greater (P < 0.05) during the 6th h of CW on day 3. Metabolic heat production during CW was similar among trials. Warmer skin temperatures during CW after days 3 and 7 indicate that vasoconstrictor responses to cold, but not shivering responses, are impaired after multiple days of severe physical exertion. These findings suggest that susceptibility to hypothermia is increased by exertional fatigue.

Lactic acid accumulation in cardiac patients performing circuit weight training: implications for exercise prescription.

OBJECTIVE: Because blood lactic acid (LA) levels may be important in prescribing exercise for cardiac patients, this study documented the LA response to four different circuit weight training (CWT) protocols and compared these responses to both maximal treadmill and LA threshold values. DESIGN: Intervention study following a crossover trial design. SETTING: A phase III community-based setting. PATIENTS: All subjects had documented cardiac disease and were volunteers. INTERVENTIONS: We used 40% and 60% of the one-repetition maximum (1-RM) for six exercises and 30 or 60sec of rest between each station, resulting in four protocols, performed in random order. A discontinuous treadmill test was conducted, and the LA threshold was determined. MAIN OUTCOME MEASURE: The main dependent variable was LA after each CWT protocol. RESULTS: No signs or symptoms suggestive of cardiovascular distress during any of the four CWT protocols were reported. A repeated-measures analysis of variance showed that the LA threshold value was significantly less than all four CWT protocols (p < .05). The CWT responses were also compared with the traditional LA threshold value of 4.0mmol/L, and both 60% protocols were significantly elevated (p < .05). CONCLUSION: Because no positive signs or symptoms were reported, we recommend starting stable cardiac patients on a CWT program with an initial load between 40% and 60% 1-RM and allowing at least 60sec of rest between exercises.

Circuit weight training in cardiac patients: determining optimal workloads for safety and energy expenditure.

BACKGROUND: While most studies suggest circuit weight training (CWT) to be safe in cardiac rehabilitation populations, few investigators have controlled variables known to impact CWT intensity. Therefore, the purposes of this study were to determine the energy cost and evaluate safety of cardiac patients while varying rest interval duration and lifting load in a CWT format. METHODS: Nine male subjects with documented coronary artery disease had maximal oxygen uptake (VO2max), one-repetition maximum (1-RM), and body composition tested. In random order and on separate days, 4 CWT sessions using either 40% or 60% of the 1-RM, and either 30 or 60 seconds of rest between stations were completed. Energy cost, heart rate (HR), blood pressure (BP), and rate-pressure product (RPP) were measured. Data were analyzed with a repeated measures analysis of variance, and Tukey's post-hoc test was performed when significant results were found. The alpha level was set at < .05. RESULTS: Subjects exercised at 25% to 32% of VO2max (58%-67% of HRmax) during CWT. The HR and RPP responses were lower during all CWT protocols than at 85% of the treadmill VO2max. No subject displayed any ST-segment depression or angina during CWT. The 40%-60-second protocol had an energy cost (2.98 kcal/min) that was lower (P < .05) than the other protocols (3.48-3.81 kcal/min). Increasing the lifting load resulted in increases (P < .05) in energy cost, and decreasing the rest interval increased energy cost only during the 40% 1-RM protocols. CONCLUSIONS: Results indicate that CWT protocols of varied intensity are safe for cardiac patients when compared to treadmill exercise, and changes in rest interval duration and load can impact the energy cost.