Impact of individual and work factors on the heat-related consequences among power plant workers in a hot region.

Prolonged exposure to hot environments increases the probability of heat load that may cause occupational heat strain to workers. This study investigates the impact of individual and work-related factors on the heat-related consequences among power plant workers in a hot region. This cross-sectional study was conducted in 2020. The collecting data tool was a validated self-reported 26 item questionnaire and completed in 534 individuals. We used logistic regression, Adjusted odds ratio (AOR) and maximum likelihood evaluations for data analysis. The findings indicated that age, work environment, physical work demands and drinking fluids during work hours are significant with heat exposure perception, heat-related symptoms, and work performance (P-value<0.05). Further, the male workers aged 40-49 are more prone to heat-related symptoms (AOR 1.34, 95% CI 1.18-2.13). The importance of addressing heat stress in occupational settings is necessary and informing strategies to help workers adapt to heat in hot workplaces.

Main social vulnerability indicators in the COVID-19 pandemic in Iran.

Background: Social factors play the main role in the vulnerability of exposed countries to disasters. The COVID-19 pandemic as a disaster is not an exception to this fact. This study aimed to determine the main social vulnerability indicators in the COVID-19 pandemic in Iran. Methods: This study was conducted during the period of 2021-2022 in three phases, including a systematic review, a virtual panel expert, and the Analytical Hierarchy Process. First, the draft of social vulnerability indicators in COVID-19 was extracted through a systematic review. Then, the extracted indicators were finalized and prioritized by the expert panel and the AHP, respectively. Results: Initially, the literature review found five domains and 38 indicators of social vulnerability in COVID-19. The outcome of the expert panel increased the related domains to six but decreased the indicators to 31. The three prioritized social vulnerability indicators that were determined by the AHP were population density, accessibility to healthcare facilities, and relevant services and vulnerable groups. Conclusion: Measuring social vulnerability with the identified indicators is valuable for addressing high COVID-19 incidence among socially vulnerable hotspot areas. Regarding the result of this study, further research should be conducted to validate the identified indicators.

Occupational health risk assessment of airborne formaldehyde in medical laboratories.

The professional use of formaldehyde is a major occupational health concern in medical laboratory operations. Quantification of various risks associated with chronic exposure to formaldehyde may help in understanding the related hazards. This study designed to assess the health risks associated with inhalation exposure to formaldehyde involving biological, cancer, and non-cancer risks in medical laboratories. This study was performed in the hospital laboratories at Semnan Medical Sciences University. Risk assessment was performed in pathology, bacteriology, hematology, biochemistry, and serology laboratories with 30 employees, using formaldehyde in their daily routine operations. We determined area and personal exposures to airborne contaminant, applied standard air sampling, and analytical method recommended by National Institute of Occupational Safety and Health (NIOSH). We addressed formaldehyde-specific hazard by estimating peak blood level, life cancer risk, and the hazard quotient of non-cancer risks, adapted from Environmental Protection Agency (EPA) assessment method. The airborne formaldehyde concentrations in the laboratory personal samples ranged 0.0156-0.5940 ppm (mean = 0.195 ppm, SD = 0.048) and area exposure ranged 0.0285-1.0810 ppm (mean = 0.462 ppm, SD = 0.087). Based on workplace exposure, peak blood levels of formaldehyde were estimated at minimum 0.0026 mg/l to maximum 0.152 mg/l (mean = 0.015 mg/l, SD = 0.016). The mean cancer risk levels in terms of area and personal exposures were estimated respectively at 3.93 E - 8 µg/m3 and 1.84 E - 4 µg/m3, and for the non-cancer risk levels of the same exposures measured respectively at 0.03 µg/m3 and 0.07 µg/m3. Formaldehyde levels were significantly higher among laboratory employees, especially bacteriology workers. Exposure and risk could be minimized by strengthening control measures including the use of management controls, engineering controls, and respiratory protection equipment to reduce exposure levels of all workers to less than the allowed exposure limits and improve indoor air quality in the workplace.

Atorvastatin prevents cadmium-induced renal toxicity in a rat model.

In many industrial processes, worker exposure to cadmium causes kidney damage; thus, protection against cadmium toxicity is important in workplace health. Cadmium toxicity involves oxidative stress by increasing the levels of reactive oxygen species. Statins have shown antioxidant effects that might prevent this increase in oxidative stress. We investigated the potential effects of atorvastatin pretreatment in protecting experimental rats against kidney toxicity caused by cadmium. Experiments were performed on 56 adult male Wistar rats (200 ± 20 g), randomly assigned to eight groups. Atorvastatin was administered by oral gavage for 15 days at 20 mg/kg/day, starting 7 days before cadmium chloride intra-peritoneal administration (at 1, 2, and 3 mg/kg) for 8 days. On day 16, blood samples were collected, and kidneys were excised to evaluate the biochemical and histopathological changes. Cadmium chloride significantly increased malondialdehyde, serum creatinine, blood urea nitrogen, and decreased superoxide dismutase, glutathione, and glutathione peroxidase levels. Pre-administration of rats with atorvastatin at a dose of 20 mg/kg decreased blood urea nitrogen, creatinine, and lipid peroxidation, increased the activities of antioxidant enzymes, and prevented changes in physiological variables compared with animals that were not pretreated. Atorvastatin pretreatment prevented kidney damage following exposure to toxic doses of cadmium. In conclusion, atorvastatin pretreatment in rats with cadmium chloride-induced kidney toxicity could reduce oxidative stress by changing biochemical functions and thereby decreasing damage to kidney tissue.

Prediction of time in industrial chemical accidents: A survival analysis.

BACKGROUND: Chemical accidents have imposed casualties and high economic and social consequences to Iranian industries and society. OBJECTIVE: This study investigated the effect of risk factors involved in occurrences of the chemical accidents and predicted the time of occurrences in Iranian chemical factories. METHODS: A cross-sectional study was implemented in 574 chemical facilities with more than 25 employees from 2018 to 2020. Collecting data instruments were 2 checklists with 15 and 25 three-point Likert scale questions, respectively. Chi square and Monte Carlo tests assessed the relationships between independent risk factors and dependent hazardous chemical accidents. Cox semi-parametric and log-normal parametric models were used to predict the upcoming time of chemical accidents based on the impacts of risk factors understudy. Data analyses were performed using Stata and R software. RESULTS: The results showed that safety data sheets, labeling, fire extinguishing system, safe chemicals storage, separation, loading, transportation and training were statistically significant with occurrences of the chemical accidents (P-value < 0.05). Loading and transportation were mostly related to chemical incidents and reduced significantly the expected time of chemical events (P-value = 0.028). CONCLUSION: Establishing a comprehensive chemical accidents dataset and strict governmental supervision on chemical safety regulations are suggested to decrease the chemical accidents at regional and local levels in chemical plants.

Working conditions and stressors data during Covid-19 and mental well-being in Iranian healthcare workers.

The current Covid-19 pandemic has affected the physical and mental stressors of hospital-based healthcare workers, but the extent of such effects are required to be quantified. This survey looked at data on nurses' perception across teaching hospitals to assess the impacts of Covid-19 on working conditions, exposure to stressors, and mental health symptoms. We implemented a population survey with a cross-sectional design in teaching hospitals affiliated with Medical Sciences Universities in Iran from April to November 2021. Participants were about 1200 health care workers, including hospital nursing staff, assistants, and technicians. Final data were assembled from 831 hospital nurses across surgery, dialysis, intensive care, emergency care, cardiac care, internal medicine, gynecology, and pediatric wards. Self-reported data were collected directly from survey participants. We collected information on variables including gender, marital status, employment status, occupational health training, evaluation of work environment stressors, fear of Covid-19, and occupational burnout constructs, specifically reflecting emotional exhaustion, depersonalization, and personal accomplishment. Focus groups of faculties evaluated and edited items to test the content wording and to define the content that are valid measures of the variables. The questionnaires were assessed for their reliability. Manual data entries were double-checked for errors. Data were recorded and categorized consistently to ensure the replicability of the data in the future. Statistical descriptive and analytical analyses were performed on the data. Data reported on the frequencies and mean values of responses and the variations of mental health in terms of worktime schedules. Chi- square, ANOVA, and correlation analyses determined relations between variables. The compiled data shed light on the exposure and response to physical and psychosocial factors and mental health symptoms among nurses during the pandemic. The data files detailed in this article can be further reused to inform workplace determinants of health in hospital settings. The obtained scores and existing dataset on mental health outcomes can help future studies to consider resilience strategies that should be provided among nurses.

Dataset on biochemical markers and histological alterations in rat kidney intoxicated with cadmium chloride and treated with antioxidant.

This dataset demonstrates the in vivo renal histology and biochemical activity of Atorvastatin (AT) in cadmium-induced nephrotoxic rat model. Fifty-six adult male Wistar rats assigned to eight groups. Rats were treated with physiologic saline at a volume of 4 mg/kg, contained Atorvastatin at a dose of 20 mg/kg body weight for 15 days. The intraperitoneal administration of cadmium chloride at doses of 1, 2, 1 and 3 mg/kg started on day 8. On day 16, samples were collected for biochemical and histological analyses. Data of renal function were estimated in the serum and organ. Cadmium chloride increased malondialdehyde (MDA), blood urea nitrogen (BUN), and creatinine (Cr) serum level and decreased superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione (GSH) levels. Administration of Atorvastatin significantly increased lipid peroxidation and renal decreased glutathione and antioxidant enzymes activity and significantly decreased BUN and Creatinine levels. Data were supported by histological examination indicated improved changes and kidney protective potential following cadmium chloride-induced oxidative stress.

Implementation of Chemical Health, Safety, and Environmental Risk Assessment in Laboratories: A Case-Series Study.

Introduction: Characterizing risks associated with laboratory activities in universities may improve health, safety, and environmental management and reduce work-related diseases and accidents. This study aimed to develop and implement a chemical risk assessment method to determine and prioritize more hazardous chemicals in the academic laboratories. Methods: A case-series study was conducted at five academic laboratories and research facilities of an Iranian medical sciences university in 2021. A risk assessment was developed and implemented in three phases to identify, evaluate, and classify potential risks and hazards. The approach provided an innovative tool for evaluating and prioritizing risks in chemical laboratories. Hazards were classified on a five-level scale. The technique reviewed both quantitative and qualitative data and pieces of evidence using Laboratory Safety Guidance (OSHA), Occupational Hazard Datasheet (ILO), the standards of the American Conference of Governmental Industrial Hygienists (ACGIH), International Agency for Research on Cancer (IARC), and National Fire Protection Agency (NFPA) codes. Results: Overall, the frequency of risks rated from "moderate" to "very high" levels was determined for the health hazards (9.3%), environmental hazards (35.2%), and safety hazards (20.4%). Hydrochloric acid had a high consumption rate in laboratory operations and received the highest risk levels in terms of potential hazards to employees' health and the environment. Nitric acid, Sulfuric acid, Formaldehyde, and Sodium hydroxide were assessed as potential health hazards. Moreover, Ethanol and Sulfuric acid were recognized as safety hazards. We observed adequate security provisions and procedures in academic laboratory operations. However, the lack of awareness concerning health, safety, environmental chemical hazards, and inappropriate sewage disposal systems contributed to the increasing levels of laboratory risk. Conclusions: Chemicals used in laboratory activities generate workplace and environmental hazards that must be assessed, managed, and risk mitigated. Developing a method of rating health, safety, and environmental risks related to laboratory chemicals may assist in defining and understanding potential hazards. Our assessment suggested the need for improving the risk perception of individuals involved in handling chemicals to prevent exposure from workplace duties and environmental pollution hazards.

Occupational Burnout Symptoms and Its Relationship With Workload and Fear of the SARS-CoV-2 Pandemic Among Hospital Nurses.

Introduction: The pandemic has intensified physical and psychological work demands experienced by nurses in a hospital environment. The purpose of this study was to examine personal and work environmental risk factors associated with occupational burnout among hospital nurses. Methods: We conducted a cross-sectional from April to November 2020. Data from 831 nurses who worked professionally in four educational hospitals were compiled through survey questionnaires to report the prevalence of burnout, occupational and individual factors. Independent t-test and Mann-Whitney test measured the link between the scopes of occupational burnout and risk factors. Results: About half of the participants indicated moderate symptoms of burnout. The fear of the nurses correlated significantly with emotional exhaustion (r = 0.71, p = 0.001), depersonalization (r = 0.67, p = 0.02), and personal accomplishment (r = 0.63, p = 0.05). Mental demand (r = 0.74, p = 0.01) and effort at work (r = 0.68, 0.001) correlated significantly with emotional exhaustion (r = 0.51, p = 0.03). Conclusion: The findings indicated a high prevalence of burnout symptoms, particularly emotional exhaustion, among hospital nursing professionals. Occupational health services should consider burnout as an occupational-related condition and provide interventions to reduce workplace chronic stressors and burnout in hospitals.

Data of risk analysis management in university campuses.

OBJECTIVES: This data paper aims to provide the data set of a practical method to health, safety, and environmental risk assessment to assess and rank potential threats/hazards and to prevent and decrease the accidents and harmful consequences at an academic setting. Descriptive data on type of hazards, places, and persons at risk were collected. Quantitative data on risk probability and severity of identified hazards were determined. Additionally, the descriptive statistics and analytical tests were applied to create a concise perspective on health, safety and environmental hazards/threats situation in research location under study. The dataset further provides information on the prioritization of determined risks according to the relevant scores and levels for doing the relevant control measures to remove and mitigate the related risks. DATA DESCRIPTION: This paper provides data of comprehensive risk assessment of health, safety and, environmental hazards of academic setting. For each identified hazard, the descriptive and numeric data are available. The information about the risk level and prevention or mitigation measure related to each hazard is provided. Additionally, the statistical tests are applied for determining the relations among the variables under study. The data and methodology on risk assessment in this article may be used to manage variety of risks in higher education institutions.

Applying health, safety, and environmental risk assessment at academic settings.

BACKGROUND: Students, staff, and faculties are involved in activities that exposed them to a range of minor to severe or even fatal accidents in academic settings. Managing work environment risks is crucial to any safety and health prevention program. This study developed a risk assessment using combinations of hazards and risk factors to establish a scale of measures in a risk reduction action plan. METHODS: This cross-sectional study was conducted in an Iranian medical sciences university in 2018. A structured method of risk assessment was developed, applying a three-step procedure to identify hazards, consequences, and risk evaluation. Data were collected through detailed health, safety, and environment checklist in 38 different sites. Finally, the risks quantified, prioritized, and control measures proposed accordingly. Chi-square and correlation tests assessed how environmental factors were associated with hazard consequences. The analysis results were evaluated at the significance level of 0.05. RESULTS: The frequencies of moderate and high-risk levels were 22.7 and 2.9%, respectively. Thus, corrective measures should be considered as soon as possible and immediately for these risk groups. Facilities and functions within laboratories, library, and powerhouse were more vulnerable to serious risks. The type of hazard had associated with the sites and total risk score at the significance level of 0.05 (P-value = 0.017). Similarly, risk severity was significantly related to the sites (P-value = 0.003). Safety hazards had a statistically higher contribution to the total risk score when compared to health and environmental hazards. CONCLUSION: The study revealed complex risks and hazardous circumstances with significant variances in academic sites and activities. Universities should provide training in risk reduction programs to increase the awareness of students, staff, and faculties, which can improve life safety in a university environment.

Hepatoprotective effect of atorvastatin on Cadmium chloride induced hepatotoxicity in rats.

AIMS: Cadmium chloride has various industrial applications and considered an industrial and environmental pollutant. The aim of this study was to evaluate the effect of atorvastatin on Cadmium chloride-induced hepatotoxicity in male rats. MATERIALS AND METHODS: Fifty-six adult male rats, randomly were divided into 8 groups. Groups 1-3 were received atorvastatin (20 mg/kg) intragastrically for 15 days during which Cadmium chloride (1, 2, and 3 mg/kg) were given intraperitoneally from days 8 to 15. Groups 4-6 were as first three groups but animals were received vehicle of atorvastatin. Group 7 was received vehicle of atorvastatin and vehicle of Cadmium chloride and Group 8 was received atorvastatin and vehicle of Cadmium chloride according to timeline of other groups. On day 16, under full anesthesia, blood sampling was prepared from heart, and livers were dissected out to analyses the biochemical and histopathology studies. KEY FINDINGS: Cadmium chloride significantly increased aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) in the serum. Malondialdehyde (MDA) significantly increased and superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione (GSH) significantly decreased the in the liver following Cadmium chloride administration. Atorvastatin significantly improved the levels of MDA, SOD, GPx, GSH, but not ALT, AST, and ALP in Cadmium chloride-treated rats. In histopathological studies, atorvastatin could not improve injured liver tissues induced by Cadmium chloride. SIGNIFICANCE: Atorvastatin has beneficial effects in improving Cadmium chloride-induced antioxidative enzymes disturbance which may be contribute to improving liver function in male rats.

Occupational violence among female workers in an Iranian industrial area.

Few studies have examined violence against female workers in the industrial sector. This study explored the prevalence of various types of violence and associated factors among female workers in the industrial sector. This descriptive survey was conducted in eleven industrial sites in Kashan, Iran, from April through September 2014. We used a 78-item questionnaire to obtain data from 817 female workers. More than half of the participants reported having experienced at least one type of violence. The prevalence rates of verbal aggression, sexual harassment, and physical violence were 52.5%, 12% and 11.5%, respectively. Single female workers (adjusted odds ratio [AOR] = 2.06, 95% CI = 1.09-4.27), and age older than 35 years were (AOR = 2.37, 95% CI = 1.26-2.93) each significantly related to increased odds of verbal violence. Short duration of employment (≤ five years) was the most strongly associated factor for sexual harassment (AOR = 2.82, 95% CI = 1.7-2.94). Working the night shift was significantly associated with encountering verbal violence (AOR = 2.79, 95% CI = 1.69-3.06). The high prevalence of violence suggests that management in industrial workplaces should invest time and resources in addressing violence. Developing a reporting procedure and training programs are recommended in dealing with workplace violence risk.

Evaluation of an undergraduate occupational health program in Iran based on alumni perceptions: a structural equation model.

PURPOSE: Evaluating educational programs can improve the quality of education. The present study evaluated the undergraduate occupational health program at the Semnan University of Medical Sciences in Semnan, Iran, with a focus on the associations between alumni perceptions of the learning environment and the outcomes of the occupational health program. METHODS: A cross-sectional questionnaire survey was conducted among alumni of the undergraduate occupational health program. We asked alumni to rate their perceptions of the items using a 4-point Likert scale. The associations between alumni perceptions of the educational program and curriculum, faculty, institutional resources, and learning outcomes were modeled and described using structural equation modeling procedures. RESULTS: A descriptive analysis of alumni perceptions indicated low evaluations for the administrative system, practical and research-based courses, and the number of faculty members. We found that a structural model of the evaluation variables of curriculum, faculty qualifications, and institutional resources significantly predicted undergraduate educational outcomes. The curriculum had direct and indirect effects on learning outcomes, mediated by faculty. CONCLUSION: The findings of our study highlight the usefulness of the structural equation modeling approach for examining links between variables related to the learning process and learning outcomes. Surveys of alumni can provide data for reassessing the learning environment in the light of the professional competencies needed for occupational health graduates.

Structural equation model of interactions between risk factors and work-related musculoskeletal complaints among Iranian hospital nurses.

BACKGROUND: Statistics indicate a high risk of developing work-related musculoskeletal disorders among hospital nurses. The challenge is to understand the associations between musculoskeletal symptoms and various individual and occupational risk factors. OBJECTIVE: This study examined the direct and indirect interactions of various risk factors with musculoskeletal complaints in hospital nurses. METHOD: In a cross-sectional design, Iranian hospital nurses from Semnan University of Medical Sciences participated in a questionnaire survey reporting their perceived perceptions of various work-related risk factors and musculoskeletal symptoms. We tested our proposed structural equation model to evaluate the relations between latent and observed concepts and the relative importance and strength of exogenous variables in explaining endogenous musculoskeletal complaints. RESULTS: Measurement model fits the data relatively acceptable. Our findings showed direct effects of psychological, role-related and work posture stressors on musculoskeletal complaints. Fatigue mediated the adverse indirect relations of psychological, role-related, work posture and individual factors with musculoskeletal complaints. CONCLUSIONS: Structural equation modeling may provide methodological opportunities in occupational health research with a potential to explain the complexity of interactions among risk factors. Prevention of work-related musculoskeletal disorders among nurses must account for physical and psychosocial conditions.

Incorporation of project-based learning into an occupational health course.

OBJECTIVE: Use of an appropriate teaching approach is a major concern for faculty members who are involved in occupational health and safety academic education. The challenge is to explore teaching tools to equip students with knowledge and skills to prepare them for their practices, in which they will encounter occupational health and safety issues in various occupational settings. The current study presents the design and implementation of a team project-based learning approach for undergraduate occupational health students to examine the appropriateness and perceptions of students and educators with regard to such a learning experience. METHODOLOGY: Steps were taken to guide the educators and students through the learning process based on projects completed in teams. The research tools for collecting data were a questionnaire and semi-structured interviews with participants. RESULTS: The results illustrated that use of the proposed teaching approach as part of occupational health education may have the potential to motivate and enhance the active roles of educators and students in the learning process, and improve students' technical and social skills that are crucial for practice in the occupational health field. CONCLUSIONS: The study findings showed that project-based learning may provide a promising teaching strategy in the education and training of occupational health students. In addition, academic institutions should encourage educators to plan, introduce and evaluate the effectiveness of project-based learning.