1.
Biopharm Drug Dispos
; 11(4): 279-309, 1990.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2340347
RESUMO
The sublingual absorption of vincamine used as tracer occurs in two successive absorption steps: true sublingual absorption and absorption in the gastrointestinal tract of the drug dissolved in the saliva and not absorbed through the buccal mucosa. This is confirmed by a pharmacokinetic study and simulation. These two successive absorptions can explain the increase in the amounts of drug absorbed.