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Nutr Hosp ; 35(6): 1298-1304, 2018 Dec 03.
Artigo em Inglês | MEDLINE | ID: mdl-30525842

RESUMO

INTRODUCTION: Alzheimer's pathology is a neurodegenerative disease characterized by cognitive impairment and functional disability that causesprogressive restrictions in daily activities. The present study associates nutritional status with cognitive and clinical aspects of the elderly withmild, moderate and severe Alzheimer's disease (AD). METHODS: data from the Mini Nutritional Assessment (MNA), bioelectrical impedance (BIA), anthropometric measurements, and physical activityindicators were associated with clinical and cognitive aspects of 43 elderly patients with AD. The data were compared to a paired control group (NC) (n = 51) at a significance level of p < 0.05. RESULTS: elderly patients with AD presented lower cognitive performance, higher risk of malnutrition (p = 0.001), lower weight (t-test, p = 0.017) and body mass index (BMI) (p = 0.006), and higher sedentarity (Chi-square, p = 0.040) when compared with the NC. The elderly with AD presented significant reduction in lean body mass (LM) and increased fat mass (FM). As dementia progresses, significant impairment of nutritional indicators is observed. Elderly patients with severe AD present lower weight, BMI, MNA scores and increased body fat mass index and fat mass when compared with those with mild/moderate AD. A correlation was observed between better cognitive performance and weight, BMI, calf circumference and triceps skinfold thickness. CONCLUSION: elderly patients with AD present high sedentarity, risk of malnutrition, lower weight, BMI and LM, and increased FM. There was progressive impairment of nutritional status and cognition as the disease progressed. There is an association between the nutritional variables and cognitive aspects.


Assuntos
Doença de Alzheimer/fisiopatologia , Disfunção Cognitiva/fisiopatologia , Estado Nutricional/fisiologia , Idoso , Idoso de 80 Anos ou mais , Doença de Alzheimer/complicações , Composição Corporal , Índice de Massa Corporal , Peso Corporal , Brasil/epidemiologia , Cognição/fisiologia , Disfunção Cognitiva/epidemiologia , Estudos Transversais , Impedância Elétrica , Feminino , Humanos , Masculino , Desnutrição/epidemiologia , Avaliação Nutricional , Estudos Prospectivos , Fatores de Risco , Comportamento Sedentário
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