Spatio-temporal dynamics of vehicles: Fusion of traffic data and context information.

We present a dataset for vehicle tracking in a rural area. Specifically, in the Barranco de Poqueira region, which includes the municipalities of Pampaneira, Bubión, and Capileira in the Sierra Nevada National Park, Granada, Spain. Four Hikvision License Plate Recognition (LPR) cameras collect vehicle entries and exits to each village. Additional contextual data, including vacation calendars, vehicle origins, and socio-demographic information, enrich the dataset. The dataset comprises three files covering nine months from February to October 2022: one with raw data directly extracted from the cameras, another aggregated at the visit level and including context information, and a third aggregated by vehicles with context information. These datasets can be useful for mobility studies, urban planning, tourism, and socio-demographic analysis.

Macroeconomic lockdown and SMEs: the impact of the COVID-19 pandemic in Spain.

Abstract: The relative importance of small- and medium-sized enterprises (SMEs) and large firms is a recurrent topic in the small business economics literature. This paper presents a real and financial social accounting matrix (FSAM) capable of distinguishing the direct and indirect effects that are transferred from micro-, small, medium, and large firms to the rest of the economy. We use the hypothetical extraction method (HEM) to explore the sequence of reactions associated with shocks that arise from the COVID-19 lockdown. Using a structural model for the Spanish economy, we identify the role of different firm size categories in the aggregate gross domestic product (GDP). Our results allow us to reconcile the mixed narrative that accompanies the evaluation of the role played by these categories in economic activity by revealing that both SMEs and large firms are important for supporting economic activity. In particular, SMEs help explain 43% of the income and two-thirds of the unemployment decline caused by the COVID-19 pandemic. Our findings also show the importance of conditioning SME industrial policy to sectoral analysis. Plain English summary: The effects of the macroeconomic lockdown and its transmission to the rest of the economy differ by firm size and across sectors. Using the Spanish context for micro-, small, medium, and large firms, we distinguish the direct and indirect effects caused by the COVID-19 pandemic. The main implications are the following: (1) Research: results emphasize that SMEs and large firms are both important to support economic activity but, in order to account for the relative effects on SMEs, it is crucial to consider the specific sector that receives the disruption. 2) Policy: SMEs are an important focus of business support policies within the EU. According to our estimations, disruptions in SMEs produce larger reductions in demand. These results could support credit policies for SMEs with a strong impact on the aggregate economy due to their greater productive and financial linkages with the domestic economy.

Treatment results of 23 cases of severe aplastic anemia with lymphocytapheresis

We report the results of 23 patients with aplastic anemia (AA) treated with a program of 14 lymphocytapheresis (LC). Treatments were performed with apheresis machines, models Haemonetics 30-S and Baxter CS3000, using the standard program. This procedure was done because AA in many cases appears as a result of the action of a T cell population that inhibits hematopoiesis. Theorically, removal of this clonal population would produce hematopoietic recovery. Of the total of 23 patients, 9 were excluded for final evaluation of treatment results because 7 died during or shortly after treatment (0.7-3 months); one patient abandoned treatment after three LC and another died 7 months later because of transformation to acute leukemia. The ramaining 14 patients were included in the final evaluation of treatment; seven females and seven males, average age 46.1 years (range 22-69); 13 with severe, and one with moderate AA; 11 with recently diagnosed, and 3 with chronica AA; 12 without previous treatment and two treated before with antilymphocyte globulin + oxymetholone (OXN) + cyclosporine A (CsA) with transiet partial remission (PR). Besides lymphocytapheresis, 13 patients received OXM; 4 of them GM-CSF ad one low dose CsA. Four patients had complete remission lasting >59.5 months (range 42-78); eight PR (average duration of >38.6 months), and two minimal remission (>37 and 29 months). Platelet, reticulocyte and granulocyte counts increased on average at 48.7, 73.3 and 91.4 days, respectively. In cocnlusion, 14 (60.8 perecent) of 23 patients with AA showed an improvement related to LC treatment, with a survival probability of 63 percent from the fourth month, the latter with and added beneficial effect of the other therapies used. Larger numbers of patients have to be treated with LC to determine its real usefulness, mechanism of action and the best conditions for its use

Trasplante de médula ósea: Aspiración múltiple de la médula ósea para trasplante en pacientes de anemia aplástica grave / Bone marrow transplant: multiple aspiration of bone marrow for transplant in patients with severe aplastic anemia

El presente trabajo describe los resultados del procedimiento empleado para obtener los injertos de médula ósea (MO) administrados a enfermos con anemia aplástica grave. En los años de 1980 a 1984, se realizaron en el Hospital General del C.M.N. del IMSS, cuatro aspiraciones múltiples de la MO en tres donadores sanos, hermanos con antígeno de histocompatibilidad (HLA) compatibles de los pacientes. Para tal fin se utilizó la técnica descrita por Thomas y Storb en 1970 la que permitió obtener sin reacciones indeseables, ni modificaciones en los índices hematológicos en la sangre periférica de los donadores, un número suficiente de células nucleadas para el trasplante. En dos enfermos el Injerto prendió y sólo en uno se observó el rechazo del injerto en dos ocasiones sucesivas lo que ocurrió al parecer por un mecanismo inmunología). Se refiere detalladamente el procedimiento empleado y se discuten los factores que modifican su rendimiento; finalmente, se consideran las condiciones que contribuyen a mejorar los resultados del trasplante de médula ósea.