RESUMO
Clinical and cytochemical study of the wound exudate neutrophilic granulocytes (NG) in patients with maxillofacial phlegmons treated traditionally and with leukinferon (immunomodulator) added to basic therapy demonstrated a positive clinical effect and pronounced stimulation of NG in the patients treated with leukinferon. The time course of cytochemical parameters of NG cytoplasm and chromatin activity was principally different in the two groups of patients. A new tissue index of NG was developed, giving an accurate integral picture of the total biological activity of the wound exudate NG.
Assuntos
Adjuvantes Imunológicos/uso terapêutico , Celulite (Flegmão)/tratamento farmacológico , Citocinas/uso terapêutico , Interferon Tipo I/uso terapêutico , Neutrófilos/efeitos dos fármacos , Adjuvantes Imunológicos/farmacologia , Adulto , Núcleo Celular/efeitos dos fármacos , Celulite (Flegmão)/imunologia , Celulite (Flegmão)/patologia , Cromatina/efeitos dos fármacos , Citocinas/farmacologia , Citoplasma/efeitos dos fármacos , Combinação de Medicamentos , Exsudatos e Transudatos/citologia , Exsudatos e Transudatos/efeitos dos fármacos , Exsudatos e Transudatos/imunologia , Face , Histocitoquímica , Humanos , Interferon Tipo I/farmacologia , Maxila , Pessoa de Meia-Idade , Neutrófilos/ultraestrutura , Estimulação Química , Resultado do Tratamento , Cicatrização/efeitos dos fármacosRESUMO
The paper presents observational data of depression extent among general patients. Psychosomatic disorders are considered in the article. The authors analyzed the mental disorders incidence among different groups of somatic patients, a problem of using the various treatment techniques in these groups. Authors propose the treatment of depression observed among general patients; it is based on literature data and their own observations.
