[The Institutionalization of Traumatology and Orthopedics in Russia].

The article considers process of institutionalization of Russian traumatology and orthopedics. It is demonstrated that process of institutionalization goes on in undulating manner takes in average about 50 years, from the moment of statement of a question to ultimate assignment of specialty of traumatology and orthopedics, organization of institutes and chairs of traumotology and orthopedics with alternation of dominance of ducens- and mandate model. On the basis of developed criteria chronological clusters and periods. The selection of traumatology and orthopedics into independent field was related not to a transition to a new stage of development of science but to general process of increasing of differentiation and specialization in medicine.

Allergic dermatoses associated with chronic opisthorchiasis during antihelminthic therapy.

We studied skin biopsy specimens from patients with allergic dermatoses associated with opisthorchiasis. Structural changes in the epidermis and derma were presented by degenerative and destructive changes in epitheliocytes with a pronounced membranolytic component, hemodynamic disturbances in the derma, disorganization of the connective tissue, and progressive fibrosis. Combination therapy including antihelmintic drug produced a positive effect, which was associated with induction of regenerative processes in basal epidermal cells, stabilization of the basal membrane, and normalization of the dermoepidermal junction. Our findings indicate that opisthorchiasis plays an important role in the pathogenesis of allergic dermatoses.