RESUMO
Echinococcus granulosus causes hydatidosis or cystic echinococcosis in humans and livestock. In humans, this disease can be managed with surgery, percutaneous treatment, chemotherapy and/or observation. The chemotherapeutic agents used and approved for treatment of hydatidosis are benzimidazoles. Because of the difficulties in achieving successful treatment, considerable efforts have been made to find new natural compounds against hydatid disease. Beta-myrcene is a monoterpene presented in the essential oils of different plants. It is the principal component of essential oil of Rosmarinus officinalis (rosemary). The goal of the present study was to evaluate the in vitro effects of beta-myrcene against germinal cells, protoscoleces and murine cyst of E. granulosus, as well also, investigate its chemoprophylactic activity in a murine model of cystic echinococcosis. For the in vitro assays, the parasites were incubated with beta-myrcene at 10, 5 and 1 µg/mL. The treatments were dose and time-dependent, and consistent with the observed morphological alterations. In the chemoprophylactic efficacy study, the effect of beta-myrcene was similar to albendazole, the reference drug for human echinococcosis treatment.
Assuntos
Albendazol/uso terapêutico , Cistos/tratamento farmacológico , Equinococose/tratamento farmacológico , Echinococcus granulosus/efeitos dos fármacos , Monoterpenos/uso terapêutico , Óleos de Plantas/uso terapêutico , Monoterpenos Acíclicos , Animais , Células Cultivadas , Humanos , Camundongos , Modelos Animais , Óleos Voláteis/farmacologia , Óleos Voláteis/uso terapêutico , Óleos de Plantas/farmacologiaRESUMO
Organic remains attributable to one regurgitated pellet were examined. The pellet, belonging to a bird of prey and collected from a cave of Southern Patagonia, was dated at 6,540 +/- 110 yr. With standard paleoparasitological procedures, eggs of Capillaria sp. and a mite, Demodex sp., were found. The parasites found in the pellet belong to a rodent ingested by the bird. The present report constitutes the first paleoparasitological study of a regurgitated pellet.
Assuntos
Doenças das Aves/história , Capillaria/isolamento & purificação , Infecções por Enoplida/história , Aves Predatórias/parasitologia , Doenças dos Roedores/história , Animais , Argentina , Doenças das Aves/parasitologia , Infecções por Enoplida/veterinária , Conteúdo Gastrointestinal/parasitologia , História Antiga , Infestações por Ácaros/história , Infestações por Ácaros/veterinária , Paleopatologia , Doenças dos Roedores/parasitologiaRESUMO
In this note, organic remains identified as a canid coprolite were examined. The material was dated at 6540 +/- 110 B.P.; it was collected in the Perito Moreno National Park, Santa Cruz, Argentina. Paleoparasitological analysis was performed following standard procedures. Coprolite fragments were rehydrated in a trisodium phosphate aqueous solution and subjected to spontaneous sedimentation for microscope analysis. Eggs of nematodes identified as Trichuris sp., Capillaria sp., Uncinaria sp., and an ascaridid (probably Toxascaris sp.) or spirurids (presumably Physaloptera sp.), plus a cestode (Anoplocephalidae), presumably Moniezia sp., were found.
Assuntos
Canidae/parasitologia , Fezes/parasitologia , Helmintíase Animal/história , Ácaros e Carrapatos/classificação , Animais , Argentina , Cestoides/isolamento & purificação , Helmintíase Animal/parasitologia , História Antiga , Moniezíase/história , Moniezíase/parasitologia , Nematoides/classificação , Nematoides/isolamento & purificação , Infecções por Nematoides/história , Infecções por Nematoides/parasitologia , Infecções por Nematoides/veterinária , PaleopatologiaRESUMO
The presence of Bertiella mucronata and Bertiella studeri (Cestoda: Anoplocephalidae) in humans is reviewed, and international infection rates and a bibliography included. Taxonomic, biological, epidemiological, pathological, diagnostic, control, prevention and therapeutic aspects of the zoonosis are analyzed, and the increase in zoonotic potentiality of the parasitosis is discussed.
Assuntos
Infecções por Cestoides/epidemiologia , Adolescente , Adulto , Infecções por Cestoides/classificação , Infecções por Cestoides/diagnóstico , Infecções por Cestoides/fisiopatologia , Infecções por Cestoides/prevenção & controle , Infecções por Cestoides/terapia , Criança , Pré-Escolar , Saúde Global , Humanos , Pessoa de Meia-Idade , PrevalênciaRESUMO
Samples of soil were collected monthly from two ranches in the zone of Puan, Province of Buenos Aires, Argentina. The monthly distribution of males, females without eggs and females with eggs for the dominant species of oribatid mites were studied. The dominant species were Zygoribatula lata in Ranch A, and Zygoribatula elongata in Ranch B. Both species are hosts of Moniezia expansa Rudolphi, 1810 and Helictometra giardi Baer, 1927. Based on the data presented, the factors associated with transmission of these cestodes, including the role played by oribatid mites, are discussed.
Assuntos
Vetores Aracnídeos/crescimento & desenvolvimento , Infecções por Cestoides/veterinária , Ácaros/crescimento & desenvolvimento , Moniezíase/transmissão , Doenças dos Ovinos/transmissão , Animais , Vetores Aracnídeos/parasitologia , Argentina , Cestoides/fisiologia , Infecções por Cestoides/transmissão , Feminino , Masculino , Ácaros/parasitologia , Estações do Ano , Ovinos , SoloRESUMO
For the first time in Argentina, it has been shown that oribatids from the genus Ceratozetes Berlese, 1908 (Acarina:Ceratozetidae) have the potential to act as intermediate hosts of Moniezia expansa from sheep. Zygoribatula lata Hammer, 1961 (Acarina:Oribatulidae) was confirmed as a potential intermediate host of M. expansa. A comparative study of the potential effectiveness of both oribatid species as intermediate hosts of M. expansa from sheep was performed.
