Triangle Singularity as the Origin of the a_{1}(1420).

The COMPASS Collaboration experiment recently discovered a new isovector resonancelike signal with axial-vector quantum numbers, the a_{1}(1420), decaying to f_{0}(980)π. With a mass too close to and a width smaller than the axial-vector ground state a_{1}(1260), it was immediately interpreted as a new light exotic meson, similar to the X, Y, Z states in the hidden-charm sector. We show that a resonancelike signal fully matching the experimental data is produced by the decay of the a_{1}(1260) resonance into K^{*}(→Kπ)K[over ¯] and subsequent rescattering through a triangle singularity into the coupled f_{0}(980)π channel. The amplitude for this process is calculated using a new approach based on dispersion relations. The triangle-singularity model is fitted to the partial-wave data of the COMPASS experiment. Despite having fewer parameters, this fit shows a slightly better quality than the one using a resonance hypothesis and thus eliminates the need for an additional resonance in order to describe the data. We thereby demonstrate for the first time in the light-meson sector that a resonancelike structure in the experimental data can be described by rescattering through a triangle singularity, providing evidence for a genuine three-body effect.

Comparative evaluation of contemporary methods of treatment and rehabilitation of post-apoplexy patients.

The study was aimed to compare efficiency of optimized and combined treatment and rehabilitation in post-apoplexy patients, using standard therapy, cytoflavin and COBS-training. The study involved 51 patients in early (n = 25) and late (n = 26) recovery periods after CVA. Reference groups included patients in early (n = 15) and late (n = is) recovery periods, receiving basic therapy. Evaluations included thepatients' complaints change, activity index (Bartel scale), neurologic state (NIHSS scale), static and locomotory disorders intensity (M.E. Tinetti scale), ultrasound dopplerography, MALDI-TOF-TOF mass spectrometry of serum. Implementation of cytoflavin and COBS-training in CVA patients in early recovery period resulted in better life quality, decrease in neurologi deficit, less static and locomotory disorders, increased average blood velocity, RI, PI on ICA siphon and lower average blood velocity, RI, PI on MCA in comparison with reference groups and CVA patients in late recovery period. Findings are molecular groups of cellular apoptosis, autophagy, necroptosis, ER stress in serum -. explanation of additional links of cytoflavin and COBS-training action mechanism in post-apoplexy patients.

[Cytoflavine effect on exudative-destructive manifestations of lung tuberculosis in children and teenagers].

A prospective, placebo-controlled ordinary-"blind"-randomized investigation of the cytoflavine effect on roentgenological manifestations of exudative-destructive processes in pulmonary tissues in cases of tuberculosis in children and teenagers has been performed in comparison to changes in the the functional state of neutrophilic granulocytes and Micobacterium tuberculosis incidence in sputum during a standard four-months course of antituberculosis therapy. It is estasblished that the administration of cytoflavine at the beginning of antituberculosis complex therapy (10 mL per 24 hours, for 5 days) results in rapid suppression of exudative-destructive disease manifestations and quick cavity repair in tuberculosis-affected areas, at an increase in the probability of outcome with "small post-tuberculosis changes". The rapid suppression of exudative-destructive processes in patients having received cytoflavine was caused by its optimizing influence on phagocytic blood capacity and did not depend on the development of abacillarity in patients.

[Sodium intoxication with fatal outcome caused by peritoneal lavage with hypertonic solution of NaCl].

We report a case of fatal sodium poisoning due to the unintentional use of 20% hypertonic saline serum during peritoneal lavage after intestinal resection. The patient presented with unconsciousness, metabolic acidosis, and plasma sodium concentration of 193 mE/l. After 3 hours, he developed paroxysmal supraventricular tachycardia, hyperthermia, generalized tonic-clonic convulsions, disseminated intravascular coagulation, and adult respiratory distress syndrome. The patient died 15 hours after the operation. Pathological examination revealed cerebral and lung oedema, pericentral hepatic necrosis, and fibrin thrombi in the lungs, stomach, and kidneys. We review, in addition, other reported cases of sodium poisoning.

[Use of hypertonic sodium chloride solution for correction of arterial hypotension in patients with endogenous intoxication]. / Primenenie gipertonicheskogo rastvora khlorida natriia v korrektsii arterial'noi gipotenzii u bol'nykh s éndogennoi intoksikatsiei.

Reaction to infusion of 7.5% sodium chloride solution was studied in 81 patients with endogenous intoxication during development of critical arterial hypotension which could not be prevented or arrested by routine high-dose therapy. The reaction was considered adequate on condition that arterial pressure increased no higher than the safe level, subsequent maintenance of hemodynamics was effective, toxin binding with plasma albumin was increased, diuresis increased, and hypernatriemia was transitory in the presence of general improvement of patient's status. Such a reaction was observed in 83% patients. The efficiency of this method is determined by indications for low-dose therapy and probability of adequate reaction to infusion.