[The role of hemosorption in preventing and treating pulmonary disorders in patients with peritonitis and acute intestinal obstruction]. / Rol' gemosorbtsii v profilaktike i lechenii legochnykh rasstroistv u bol'nykh peritonitom i ostroi neprokhodimost'iu kishechnika.

An analysis of treatment and examination of 80 patients with peritonitis and acute intestinal obstruction of different etiology has been made when hemosorption was used for struggle against intoxication. It has been shown that hemosorption possessing a potent detoxicating effect considerably facilitates activation of the non-gas-exchange functions of the lungs. However, losses of the surfactant synthesis components during hemocarboperfusion as well as absorption of oxygen by certain sorts of charcoal (SKN-4M, SKN-1K) results in arterial hypoxemia. For prophylactics and treatment of pulmonary disorders in patients with peritonitis and acute intestinal obstruction hemosorption must be supplemented with repeated sessions of spontaneous respiration with positive pressure at the end of breathing out.

[Toxemia syndrome in patients with acute intestinal obstruction]. / Sindrom intoksikatsii u bol'nykh ostroi kishechnoi neprokhodi- most'iu.

The results of examination and treatment of 216 patients with acute intestinal obstruction of benign genesis are discussed. The values of blood plasma toxicity and the values of hemostasis determined before and after the operation were compared. Intoxication of patients was found to increase in the postoperative period. Its increase was appraised according to the duration of the disease. The causes of mortality were analysed and the risk factors of intoxication increase in the postoperative period were revealed. The authors suggest a classification of the phases of intoxication in patients with acute intestinal obstruction on the basis of the degree of intoxication and the condition of homeostasis.

[Functional state of the lungs in toxemia in peritonitis and acute intestinal obstruction]. / Funktsii legkikh v usloviiakh intoksikatsii pri peritonite i ostroi neprokhodimosti kishechnika.

On the basis of examination of 214 patients, it was established that the pronounced intoxication syndrome developing in peritonitis and acute ileus led to disorders in the non-respiratory pulmonary functions. This contributes to the development of arterial hypoxemia, hypocapnia and acute respiratory failure. In the complex of treatment of the patients, it is expedient to use extracorporeal desintoxication.

[Effect of postoperative hemosorption on pulmonary function in patients with acute intestinal obstruction]. / Vliianie posleoperatsionnoi gwemosorbtsii na funktsii legkikh u bol'nykh s ostroi neprokhodimost'iu kishechnika.

The effect of postoperative hemosorption (HS) on the pulmonary functions in 55 patients with acute ileus was studied. The severity of the state of the patients was conditioned by intoxication leading to ++over-stress of the non-respiratory pulmonary functions and development of I-II stage acute respiratory failure. HS contributes to detoxication of an organism, but is accompanied by the mean 30-35% loss of the oxygen on the adsorbent resulting in development of arterial hypoxemia. Thus, HS should be added with spontaneous breathing with positive pressure at the end of expiration.

[Fibrin-stabilizing factor and its significance in the surgical treatment of patients with obstructive jaundice]. / Fibrinstabiliziruiushchii faktor i ego znachenie pri khirurgicheskom lechenii bol'nykh s obturatsionnoi zheltukhoi.

The fibrin-stabilizing factor (XIII factor of the hemostasis system) was studied in 101 patients with unresolved mechanical jaundice. It was first shown that this disease is characterized by a statistically significant decrease of the FSF to 56-68%. The decrease of the XIII factor is prognostically unfavourable and points to the development of hepatic insufficiency. The experience has shown that in critical patients with the content of FSF lower than 30% it is expedient to perform decompressive procedures such as cholecystostomy, percutaneous transhepatic cholangiostomy, endoscopic papillotomy etc. as well as transfusion of fresh frozen plasma and hemosorption if there is no contraindications. In patients with FSF lower than 50% before operation it is sufficient to perform hemosorption and transfusion of fresh frozen plasma.

[Microcirculatory disorders of the arm in post-mastectomy edema]. / Mikrotsirkuliatornye narusheniia v verkhnei konechnosti pri postmastéktomicheskikh otekakh.

Microcirculation disorders have been examined in 125 patients with postmastectomy edemas of the arms by the following methods: indirect radionuclide lymphography, phlebography, capillaroscopy, radionuclide examination of the microcirculation, measurement of the tissue pressure, morphologic examination of the skin and subcutaneous fat. The studies have made it possible to single out four principal stages of the microcirculatory disorders: functional, reversible, progressing, and decompensation. A correlation between the edema severity and the stage of the disorders has been revealed. Microcirculation changes have been related to the development of hypoxia, dystrophic changes aggravating the process. Administration of antioxidants and antihypoxants (prodectin, trental, vitamin E) for the correction of microcirculatory disorders has improved the immediate results of therapy.