[An index of blood neutrophil injury in man and animals immunized with live anthrax vaccine]. / Pokazatel' povrrzhdeniia neitrofilov krovi u liudei i zhivotnykh, immunizirovannykh zhivoi sibireiazvennoi vaktsinoi.

The authors present the results of study of the blood neutrophil injury in guinea pigs, rabbits, monkeys, and also humans inoculated subcutaneously with live anthrax vaccine. Along with intradermal test with anthraxin, the mentioned test is suggested to assess the immunological status of persons immunized with anthrax vaccine.

[Preparation and study of the anthrax protective antigen. II. Development of test preparations for the assessment of the quality of anthrax chemical vaccines and of the antigens obtained at various stages of its preparation]. / Poluchenie i izuchenie sibireiazvennogo protektivnogo antigens. Soobshchenie II. Test-preparaty dlia otsenki kachestva sibireiazvennoi khimicheskoi vaktsiny i antigenov, poluchaemykh na stadiiakh ee prigotovleniia

A homogeneous anthrax protective antigen (from the ST-I strain) characterized by a high immunogenicity and stability was obtained. Hyperimmune, monospecific to this preparation antiserum was prepared. It is suggested that these preparations can be used for the assessment of the quality of the anthrax chemical vaccine and of the antigens obtained at various stages of its preparation.

[Production and study of anthrax antigen. I. Nutrient medium for production of native anthrax protective antigen]. / Poluchenie izuchenie sibireiazvennogo antigena. Soobshchenie I. Pitatel'naia sreda dlia polucheniia nativnogo sibireiazvennogo protektivnogo antigena

The authors present the results of studies concerning the choice of nutrient bases and elaboration of a medium for obtaining anthrax protective antigen providing an active preparation. Filtrates of crude cultures obtained on the nutrient medium prepared of 3% hydrochloric hydrolyzate of fish flour, corn extract, glucose, sodium bicarbonate and mineral salts proved to be the most active. Tests for determination of usefulness of the culture fluids with the maximum content in them of the protective antigen are recommended.