[Influence of perhexiline maleate on the electrocardiographic signs of myocardial ischemia. Ergometric study]. / Influence du maleate de perhexiline sur les signes electrocardiographiques de l'ischemie myocardique. Etude ergométrique

The improvement in the electrocardiographic signs of coronary insufficiency under the influence of perhexiline maleate is the object of an ergometric study in 28 patients. Ergometric tests repeated at regular over an average period of 8.3 months show a rapid ECG improvement, sustained over the period of the study. The heart rate, registered while at rest, which diminshes between that noted at the beginning of the study and that noted at the first registration under treatment, remains stable during the three following registrations. At the end of the effort, on the other hand, a significant reduction in tachycardia is observed during all the registrations.