Psychodermatology in clinical practice: An examination of physician attitudes, beliefs, and interventions toward psychocutaneous disease.

Fifteen days postconception, the embryonic ectoderm simultaneously gives rise to the central nervous system and the epidermis of the integumentary system. The connections between the two organ systems manifests in both the psychiatric and dermatologic setting. To examine the current awareness of psychiatric comorbidity in dermatologic practice and its management in a sample of dermatologists across the United States. A survey was conducted that explored physician perspective on psychiatric comorbidity, clinical practice, and management, that is, use of survey screening measures, employment of psychological interventions, and coordination with mental health services. SPSS v25 was used for descriptive statistical analysis and to calculate Pearson's correlation coefficients between familiarity with dermatologic/psychiatric comorbidity and its management. Ninety-eight percentage of respondents believed a relationship between mental and dermatological health. 61.7% of respondents reported seeing patients with known psychological problems more than once a week. The administration of a psychiatric questionnaires was noted in 23% of practices and only 6.38% administer the questionnaire at every appointment. Management of comorbid disease is best done through the collaboration of dermatology and psychiatry. Implications for streamlining practice include the routine administration of quality of life surveys, utilization of brief psychotherapeutic strategies, and regular interdisciplinary referrals.

A Systematic Review of DNA Methylation and Preterm Birth in African American Women.

BACKGROUND: The causes of many cases of preterm birth (PTB) remain enigmatic. Increased understanding of how epigenetic factors are associated with health outcomes has resulted in studies examining DNA methylation (DNAm) as a contributing factor to PTB. However, few studies on PTB and DNAm have included African American women, the group with the highest rate of PTB. METHODS: The objective of this review was to systematically analyze the existing studies on DNAm and PTB among African American women. RESULTS: Studies ( N = 10) were limited by small sample size, cross-sectional study designs, inconsistent methodologies for epigenomic analysis, and evaluation of different tissue types across studies. African Americans comprised less than half of the sample in 50% of the studies reviewed. Despite these limitations, there is evidence for an association between DNAm patterns and PTB. CONCLUSIONS: Future research on DNAm patterns and PTB should use longitudinal study designs, repeated DNAm testing, and a clinically relevant definition of PTB and should include large samples of high-risk African American women to better understand the mechanisms for PTB in this population.