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1.
Am J Orthod Dentofacial Orthop ; 161(2): e114-e126, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34625316

RESUMO

INTRODUCTION: The purpose of this study was to determine if written rehearsal of informed consent improved 6-month recall and comprehension compared with the current best practices. METHODS: A consultation was provided and subjects read the modified informed consent document. They were randomized to group A (received the core and up to 4 custom elements of treatment, wrote what each image displayed) or group B (presentation of the 18 elements with core elements chunked at the end followed by up to 4 custom elements). Interviews recording knowledge recall/comprehension occurred immediately and after months later. RESULTS: Overall, no significant differences in baseline or 6-month follow-up scores were found between groups. Initially, group A outperformed group B in some core domains. There were no significant differences between groups in the change of scores from initial to follow-up. Follow-up scores were significantly lower than baseline scores (P <0.05). Higher initial scores were associated with larger drops at follow-up. A decrease in knowledge >20% was common. CONCLUSIONS: Overall the methods are comparable at baseline and 6-months. Initial content retention was roughly 60+%, with 6%-9% deterioration. For areas of treatment methods, risk, discomfort, and resorption at 6-months, the current processes failed the patient and left the practitioner vulnerable to risk management issues. Results support the rehearsal method with immediate feedback for misunderstandings as the preferred method for informed consent.


Assuntos
Compreensão , Termos de Consentimento , Humanos , Consentimento Livre e Esclarecido , Rememoração Mental , Projetos de Pesquisa
2.
Pediatr Dent ; 41(2): 132-135, 2019 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-30992111

RESUMO

Purpose: The purpose of this study was to determine if dental ages are more advanced in overweight children and influenced by genetic variation. Methods: Panoramic radiographs from 577 children were obtained. For performing genetic studies, an additional 236 subjects had panoramic radiographs and whole saliva samples collected. Genotyping of IGF, FGF, and FGFR markers was done. Dental age was determined in 177 patients utilizing Demerjian's method and panoramic radiographs. Skeletal maturation was determined in 28 patients using Baccetti's cervical vertebral maturation method on lateral cephalograms. PLINK was used to test for over-representation of alleles. Results: FGF7, FGF10, and FGF13 were significantly associated with obesity (P = 0.02). When dental age was considered, overweight and obese children are more likely to have dental ages more advanced than their chronological ages (P = 0.05). An excess of heterozygotes of FGF18 rs4073716 was found in children with dental age more advanced than their chronological age (P=0.04). Conclusions: Overweight and obese children have dental ages more advanced than their chronological ages, and this occurrence may be influenced by genetic variation in FGF18.


Assuntos
Determinação da Idade pelos Dentes , Variação Genética , Obesidade Infantil , Radiografia Panorâmica , Dente/crescimento & desenvolvimento , Determinação da Idade pelo Esqueleto , Índice de Massa Corporal , Vértebras Cervicais/diagnóstico por imagem , Criança , Pré-Escolar , Feminino , Fatores de Crescimento de Fibroblastos/genética , Marcadores Genéticos , Humanos , Masculino , Pennsylvania , Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética , Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/genética , Receptor IGF Tipo 2/genética
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