[Nalbuphine. Comparison of 2 therapeutic regimens for the control of postoperative pain]. / Nalbufina. Comparación de dos regímenes terapéuticos para el control del dolor postoperatorio.

The therapeutical efficiency and the undesirable effects of Nalbuphine administered to control postoperative pain were compared. Two groups of patients were studied: one group received 10 mg endovenously every 4 h during the first 12 h of the postoperative phase and every 6 h during the following 12 h while the other group received 20 mg with the same intervals. The following variants were evaluated: pain, systolic arterial tension, cardiac frequency, respiratory frequency and undesirable effects. After statistical analysis, a similarity in both groups was confirmed for pain, systolic arterial tension, cardiac frequency, while a significant difference was found in two of the undesirable effects: sedation and sweating. In conclusion, the 10 mg dose is as effective as that of 20 mg to control pain and has less unwanted effects.

Nalbufina. Comparación de dos regímenes terapéuticos para el control del dolor postoperatorio. / [Nalbuphine. Comparison of 2 therapeutic regimens for the control of postoperative pain]

The therapeutical efficiency and the undesirable effects of Nalbuphine administered to control postoperative pain were compared. Two groups of patients were studied: one group received 10 mg endovenously every 4 h during the first 12 h of the postoperative phase and every 6 h during the following 12 h while the other group received 20 mg with the same intervals. The following variants were evaluated: pain, systolic arterial tension, cardiac frequency, respiratory frequency and undesirable effects. After statistical analysis, a similarity in both groups was confirmed for pain, systolic arterial tension, cardiac frequency, while a significant difference was found in two of the undesirable effects: sedation and sweating. In conclusion, the 10 mg dose is as effective as that of 20 mg to control pain and has less unwanted effects.

Nalbufina: comparación de los regímenes terapéuticos para el control del dolor postoperatorio / Nalbuphine: comparison of 2 therapeutic regimens for the control of postoperative pain

Se comparó la eficacia terapéutica y los efectos indeseabeles de la Nalbufina administrada para controlar el dolor postoperatorio. Se estudiaron dos grupos de enfermos: uno recibió 10 mg E.V. c/4 horas durante 12 primeiras horas del postoperatorio y cada 6 horas en las siguientes 12 horas y el otro recibió 20 mg a iguales intervalos. Se evaluaron: dolor, tensión arterial sistólica, frecuencia cardíaca, frecuencia respiratoria y efectos indeseables. Se comprobó similitud en ambos grupos con respecto a las distintas variables y diferencia significativa en dos de los efectos indesables: sedación y sudoración. Se concluye que la dosis de 10 mg es tan efectiva como la de 20 mg para el control del dolor y tiene menos efectos indeseables (AU)

Nalbufina: comparación de los regímenes terapéuticos para el control del dolor postoperatorio / Nalbuphine: comparison of 2 therapeutic regimens for the control of postoperative pain

Se comparó la eficacia terapéutica y los efectos indeseabeles de la Nalbufina administrada para controlar el dolor postoperatorio. Se estudiaron dos grupos de enfermos: uno recibió 10 mg E.V. c/4 horas durante 12 primeiras horas del postoperatorio y cada 6 horas en las siguientes 12 horas y el otro recibió 20 mg a iguales intervalos. Se evaluaron: dolor, tensión arterial sistólica, frecuencia cardíaca, frecuencia respiratoria y efectos indeseables. Se comprobó similitud en ambos grupos con respecto a las distintas variables y diferencia significativa en dos de los efectos indesables: sedación y sudoración. Se concluye que la dosis de 10 mg es tan efectiva como la de 20 mg para el control del dolor y tiene menos efectos indeseables