1.
J Vasc Interv Radiol
; 29(7): 1057-1059, 2018 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29935786
2.
Proc (Bayl Univ Med Cent)
; 30(4): 424-426, 2017 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28966451
RESUMO
Castration-resistant prostate osseous metastases can be challenging to treat. There is a new era of clinical advancement with the Food and Drug Administration approval of radium-223 for use in these patients. Radium-223 is the only clinically used therapeutic radiopharmaceutical that emits alpha particles, making it extremely safe for therapeutic purposes for the patient as well as close contacts. This review discusses radium-223's mechanism of action, pharmacokinetics, indications, and safety profile, as well as findings of concluded clinical trials.