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Artigo em Inglês | MEDLINE | ID: mdl-21323162

RESUMO

This study was aimed to find out the host-parasite relationship between Paragonimus heterotremus isolated as metacercariae from mountain crabs, Indochinamon manipurensis, in Manipur, India and laboratory animals such as puppies, albino rats, Swiss mice, guinea pigs, and rabbits, as experimental animals. The animals were fed with the metacercariae. Infected animals were sacrificed 35 to 430 days after feeding to recover worms, which were used to determine the developmental stages. Adult worms (n = 14) were recovered from 3 puppies > or = 70 days after feeding and immature worms (n = 25) were recovered from 2 other puppies 35 or 43 days after infection. The infection rate in puppies was 100%. Juvenile worms were recovered from 3 of 13 rats: 1 of 11 rats whose viscera and cavities were examined and both of two rats whose muscles were examined. Rats were not a suitable animal model for pulmonary infection with P. heterotremus. Mice, guinea pigs, and rabbits were also found to be insusceptible to pulmonary infection with P. heterotremus.


Assuntos
Modelos Animais de Doenças , Cães/parasitologia , Paragonimíase/parasitologia , Paragonimus/isolamento & purificação , Animais , Feminino , Cobaias , Interações Hospedeiro-Parasita , Índia , Masculino , Metacercárias/isolamento & purificação , Metacercárias/parasitologia , Camundongos , Coelhos , Ratos
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