RESUMO
Productivity improvement is one of the high-priority areas in the development of solar stills. The present work describes the use of some low-cost energy storage materials such as sand, gravels, and black granite as potential candidates to improve the productivity of the tubular solar still (TSS). The experimental studies have been carried out at Nagpur (21.1241° N, 79.0023° E) to investigate the effects of these materials on the productivity of the TSS. Three separate TSS experimental setups have been made for each energy storage materials. These include (a) 5 kg of fine sand (0.125-0.25-mm grain size), (b) small gravels (20-30 mm), and (c) black granite (5-mm thickness) placed in the absorber basin of individual TSS setup, separately. The experiments have been performed by varying basin water depth at 0.5 cm, 1 cm, and 2 cm, for each case. The results show that for water depth of 0.5 cm, productivity of TSS-Black granite is enhanced by 10.5% and 34.88% as compared to TSS-Gravel case and TSS-Sand case, respectively. Thermal efficiency and exergy efficiency of TSS-Black granite at 0.5-cm water depth is enhanced by (32.4%, 9.8%) and (92.1%, 21.9%) as compared to TSS-Sand case and TSS-Gravel case, respectively. Furthermore, it has been estimated that the cost of production of freshwater using TSS-Black granite is lowest among all selected combinations.
RESUMO
AIMS: The standard of care for carcinoma cervix stage IB2-IVA is five fractions per week of radiotherapy (RT) with concurrent cisplatin. We compared the standard treatment with six fractions per week of RT with concurrent Cisplatin to see whether the later had improved survival outcomes with comparable toxicities. SETTINGS AND DESIGN: 46 patients of carcinoma cervix with stage IB2-IVAwere randomized into two arms. MATERIALS AND METHODS: Study arm: 46 Gy/23 fractions/26 days, 6 fractions/week with injection CDDP 40 mg/m2 and Control arm: 46 Gy/23 fractions/31 days, 5 fractions/week with injection Cisplatin 40mg/m2. Patients in both the arms received LDR brachytherapy to a dose of 29 Gy at point A. STATISTICAL ANALYSIS USED: The primary end points were disease-free survival (DFS) and overall survival (OS). Compliance to treatment and treatment toxicities were the secondary end points. P value ≤0.05 were considered significant. RESULTS: The study was carried out during June, 2014-April, 2015. Statistical analysis was done in May, 2019. Of 46 patients, 39 patients completed the treatment. The study and control arms had 17 and 22 patients, respectively. Median follow-up period is 45 months (range: 1-54 months). 3-year DFS rates and OS was 69.5% vs. 72.7% (P = 0.73) and 63% vs. 68% (P = 0.45) in study and in control arm, respectively. There was no significant difference in acute and late radiation toxicities between two arms. CONCLUSION: Chemoradiotherapy with six fractions per week seems feasible and equally efficacious in terms of survival outcomes and toxicity profile. Further prospective randomized controlled study is required to prove the merit of altered fractionation with concurrent cisplatin.
