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Protein Pept Lett
; 14(6): 543-51, 2007.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17627594
RESUMO
Virus neutralizing MAb binding and T helper cell stimulating peptide epitopes from structural and non-structural proteins of Japanese encephalitis virus were delineated. It was observed that priming by T helper peptides potentiated neutralizing antibody response against JE virus. Immunization with chimeric T helper - B cell peptides could thus protect mice from lethal challenge with JE virus.