RESUMO
AIM: To isolate and determine the chemical constituents of the stem bark of Cordia dichotoma (Forst f.), a plant used for medicinal purpose in folk medicine. MATERIALS AND METHODS: Petroleum ether extract of the stem bark was used for this study. Saponification process was performed to separate fatty acid and unsaponifiable matter. RESULTS: One triterpenoids, α-amyrin was isolated from the bark by using isocratic elution. The chemical compounds isolated, for the first time, were analyzed by GC/MS, IR, and UV. The chemical composition of the fatty acids methyl esters (FAMEs) in bark of Cordia dichotoma were also analyzed by gas chromatography-mass spectrometry. After methyl-esterification, 17 components were identified in the bark. The derivatization conditions were investigated in order to validate this method. CONCLUSION: The present analysis revealed that Cordia dichotoma stem bark contains 17 fatty acid. The principal themes of the review highlight the development and application of chromatographic techniques for the separation, isolation and detection of the compounds.
Assuntos
Cordia/química , Ácidos Graxos/análise , Triterpenos/análise , Ácidos Graxos/química , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Medicina Tradicional , Ácido Oleanólico/análogos & derivados , Ácido Oleanólico/análise , Ácido Oleanólico/química , Casca de Planta/química , Extratos Vegetais/química , Plantas Medicinais/química , Espectrofotometria Ultravioleta , Espectroscopia de Infravermelho com Transformada de Fourier , Triterpenos/químicaRESUMO
The present review reveals a comprehensive description of various pharmacological studies carried out on Leptadenia reticulata, a source of several active compounds, i.e. Leptadenia reticulata plant belonging to family Asclepiadaceae, it is also known as 'Jivanti', used for the treatment of various ailments in human civilization as well as used in folk medicine as a remedy in various reported herbal formulations. The plant has been found to exhibit diverse pharmacological activities like antibacterial activity, anticancer activity, lactogenic eff ect, antioxidant activity, anti-implantation activity, anti-asthmatic activity, modulating eff ect, activity of silver nano particles, hepatoprotective activity, antifungal activity, antidiabetic activity and anti-infl ammatory activity. Traditionally, the plant promotes fi tness and vigor, the tone of voice, cures eye diseases, fever, and night blindness, cough, maintain pregnancy and gangrene. In this review, we give the recent scientifi c update on this plant with therapeutic potential and discuss the methods of carrying out studies. The present review draws the attention of researchers towards the potential therapeutic activity of Leptadenia reticulata for their active constitute.
